Some Biological Compounds, Radical Scavenging Capacities and Antimicrobial Activities in the seeds of &lt;i&gt;Nepeta italica&lt;/i&gt; L. and &lt;i&gt;Sideritis montana&lt;/i&gt; L. subsp. &lt;i&gt;montana&lt;/i&gt; from Turkey

Emre, İrfan; Kürşat, Murat; Yılmaz, Ökkeş; Erecevıt, Pınar

doi:10.3989/gya.033210

Cited by 15 publications

(16 citation statements)

References 38 publications

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“…The methanol extracts of Z clinopodioides and N italica demonstrated activity only against M smegmatis (23 and 291 μg/mL, respectively). Previous studies showed that the seeds of N italica exhibit significant antimicrobial activity 46 . As demonstrated in the previous report, the ethanol extract of Z clinopodioides exhibited good antibacterial activity against Staphylococcus aureus , Staphylococcus epidermidis , Bacillus cereus and Pseudomonasa eruginosa with a high MIC value of 14.5 μg/mL, respectively 47 .…”

Section: Resultsmentioning

confidence: 66%

Biological activity, and volatile and phenolic compounds from five Lamiaceae species

Çelik

Kılıç

Kanbolat

et al. 2020

Flavour & Fragrance J

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Lamiaceae, a family of flowering plants, have been historically used as culinary herbs, shrubs and medicinal plants. With this study, the volatile organic compounds (VOCs) of the five species of the Lamiaceae family (Thymus cilicicus, Clinopodium nepeta L., Nepeta italica L., Thymbra spicata L. and Ziziphora clinopodioides) that grow in Turkey were identified by the SPME/GC‐FID/MS method. The five species were screened in order to reveal their antibacterial and antioxidant activities. Phenolic compound analyses of five species were performed by using RP‐HPLC with diode array detection. Among the total number of 73 compounds that were identified, α‐pinene (2.2%‐13.8%), β‐pinene (0.3%‐25.9%), p‐cymene (0.7%‐17.9%), γ‐terpinene (0.4%‐22.0%), carvacrol (0.1%‐40.2%), sabinene (1.2%‐34.2%), terpinen‐4‐ol (0.2%‐27.5%), (E)‐β‐caryophyllene (0.1%‐13.8%) and (E)‐β‐farnesene (0.4%‐19.7%) were found to be the most plentiful ones. The minimal inhibitory concentration (MIC) values of the methanol extracts of the five species of the Lamiaceae family were investigated, and the results were in the range of 23‐959 µg/mL; the most pronounced antibacterial activities were determined to be against Mycobacterium smegmatis (23‐291 µg/mL). All of the methanol extracts possessed effective antioxidant capacity (IC50: 1.82‐28.18 μmol/L Trolox/g sample) as estimated from the 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) radical‐scavenging assays. Additionally, the effect of phenolics, especially benzoic acid (86.27, 27.85, ‐, 13.11, 9.59 mg/g extract, respectively), on the biological properties of the methanol extracts of the five species of the Lamiaceae family, was investigated.

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Section: Resultsmentioning

confidence: 66%

Biological activity, and volatile and phenolic compounds from five Lamiaceae species

Çelik

Kılıç

Kanbolat

et al. 2020

Flavour & Fragrance J

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“…Palmitic acid (14.34%) and oleic acid (13.14%) in S. libanotica ssp. linearis ; capric acid (42.72%) and steric acid (30.64%) in S. taurica ; linolenic acid (77.04 ± 2.07%) and oleic acid (18.83 ± 0.10%) in S. montana were determined as major fatty acids (Aboutabl et al, ; Demirtas et al, ; Emre, Kurşat, & Yılmaz, ).…”

Section: Resultsmentioning

confidence: 99%

Phytochemical contents, antioxidant effects, and inhibitory activities of key enzymes associated with Alzheimer's disease, ulcer, and skin disorders ofSideritis albifloraandSideritis leptoclada

2019

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In this study, urease, tyrosinase, cholinesterase inhibitory, and antioxidant activities of various extracts of Sideritis albiflora and Sideritis leptoclada were determined together with the phytochemical contents. In addition, the fatty acid compositions and phenolic compounds were investigated by gas chromatography (GC), gas chromatography-mass spectrometry (GC-MS), and high performance liquid chromatography-diode array detector (HPLC-DAD). Rosmarinic acid and caffeic acid in both Sideritis species were identified as the most abundant phenolic compounds whereas palmitic acid was found as a major fatty acid. The acetone extract of S. leptoclada indicated the highest antioxidant activity in β-carotene-linoleic acid (IC 50 : 17.23 ± 0.11 µg/ml), DPPH • (IC 50 :28.14 ± 0.05 µg/ml) and ABTS •+ (IC 50 : 15.18 ± 0.02 µg/ml) assays. The acetone extract of S. albiflora (A 0.50 : 32.71 ± 0.44 µg/ml) was found as the best reductant in cupric reducing antioxidant capacity (CUPRAC) assay. Against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), only the hexane extracts of Sideritis species showed moderate inhibitory activity. Moreover, all extracts of S. albiflora and the hexane extract of S. leptoclada exhibited significantly higher urease inhibitory activity than that of thiourea. Further, in vivo activity studies on extracts and isolated constituents obtained from these species are needed to understand the activity in biological systems. Practical applicationsMultiple pharmacological studies have proven that Sideritis species is precious with significant bioactive properties. This is the first comprehensive research to determine the enzyme inhibitory and antioxidant activities of various extracts of S. albiflora and S. leptoclada with phytochemical contents. Both Sideritis species were found to be rich in rosmarinic and caffeic acids. The acetone extracts showed the highest activity in terms of antioxidant activity, while the hexane extracts exhibited superior urease inhibitory activity. These results show that Sideritis species could be used as urease inhibitors' agents and source of antioxidants in food, pharmaceutical, and cosmetic industries. K E Y W O R D S antioxidant activity, enzyme inhibitory activity, phenolic compounds, Sideritis albiflora, Sideritis leptoclada 2 of 11 | DEVECI Et al.

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“…Lipid-soluble vitamins were extracted from the lipid fraction according to the method of Emre [19]. e extracted lipids of seed material were dissolved in acetonitrile/methanol (75/25 v/v) and 50 mL were injected into the HPLC instrument (Shimadzu, Kyoto, Japan).…”

Section: Fatty Acid and Vitaminmentioning

confidence: 99%

Vitamin, Trace Element, and Fatty Acid Levels of Vitex agnus-castus L., Juniperus oxycedrus L., and Papaver somniferum L. Plant Seeds

Özkaya

Çiftçi

Yılmaz

et al. 2012

Journal of Chemistry

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The levels of fat-soluble vitamin, trace element and fatty acid ofVitex agnus-castusL.,Juniperus oxycedrusL., andPapaver somniferumL. seeds in Turkey were determined by using HPLC, ICP-OES, and GC, respectively. In theVitex agnus-castusL.,Juniperus oxycedrusL., andPapaver somniferumL. seeds, linoleic acid (18 : 2) was determined with the highest level rates (%54.11, %28.03, and %72.14, resp.). In theVitex agnus-castusL. seeds, R-tocopherol,α-tocopherol, and K1levels were determined as 9.70 μg/g, 18.20 μg/g, and 24.79 μg/g, respectively; In theJuniperus oxycedrusL. seeds, R-tocopherol,α-tocopherol, and K1were determined as 18.50 μg/g, 0.84 μg/g, and 5.00 μg/g, respectively, and in thePapaver somniferumL. seeds, R-tocopherol,α-tocopherol, K1, and D2levels were determined as 43.25 μg/g, 122.05 μg/g, 12.01 μg/g, and 0.62 μg/g, respectively. In theVitex agnus-castusL.,Juniperus oxycedrusL., andPapaver somniferumL. seeds, nickel (Ni), zinc (Zn), and iron (Fe) were determined with the trace element level rates (4.42 mg/kg, 10.43 mg/kg, 3.71 mg/kg for Ni, 7.00 mg/kg, 7.70 mg/kg, and 24 mg/kg for Zn and 93.73 mg/kg, 187.95 mg/kg, and 149.64 mg/kg for Fe, resp.). These parameters in seeds are very important for human life.

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Some Biological Compounds, Radical Scavenging Capacities and Antimicrobial Activities in the seeds of <i>Nepeta italica</i> L. and <i>Sideritis montana</i> L. subsp. <i>montana</i> from Turkey

Cited by 15 publications

References 38 publications

Biological activity, and volatile and phenolic compounds from five Lamiaceae species

Biological activity, and volatile and phenolic compounds from five Lamiaceae species

Phytochemical contents, antioxidant effects, and inhibitory activities of key enzymes associated with Alzheimer's disease, ulcer, and skin disorders ofSideritis albifloraandSideritis leptoclada

Vitamin, Trace Element, and Fatty Acid Levels of Vitex agnus-castus L., Juniperus oxycedrus L., and Papaver somniferum L. Plant Seeds

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