Some biological activities of pigments extracted from Micrococcus roseus (PTCC 1411) and Rhodotorula glutinis (PTCC 5257)

Abstract

The importance of replacing synthetic pigments with natural types is increasing day by day in the food industry due to the harmful effects of some synthetic pigments. Microorganisms are a major source of natural pigments, which nowadays have attracted the attention of researchers. In this study, carotenoid pigments were produced by Micrococcus roseus and Rhodotorula glutinis, and some of their biological properties such as antimicrobial, antioxidant, anticancer, and anti-inflammatory activities were evaluated. Given the results, bacteria, especially gram-positive bacteria, had higher sensitivity to the pigments extracted from M. roseus (PEM) and R. glutinis (PER) compared to molds so that Bacillus cereus and Alternaria citri had the highest and the lowest sensitivity, respectively. PER showed a higher antioxidant activity compared with PEM in the various methods of measuring antioxidant activity. In vitro and in vivo anti-tumor-promoting activities of PER were measured significantly more than PEM (P <0.05). Both pigment extracts remarkably inhibited the 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation, so that ID (50% inhibitory dose) of PEM and PER were 0.22 and 0.09 mg/ear, respectively.

Bioactivities and Extract Dereplication of Actinomycetales Isolated From Marine Sponges

“…Species of the genus Microccocus produce pigmented colonies which are sources of carotenoid pigments. Rostami et al (2016) showed that carotenoid pigments produced by Microccocus roseus proved to have some antioxidant, antitumor and potent antibacterial activities, in particular against Gram-positive bacteria. M. luteus has very few genes associated with secondary metabolism and possesses one of the smallest genomes from the phylum Actinobacteria , comprised of a single circular chromosome with 2.5 Mb in size (Young et al, 2010).…”

1H NMR and Raman spectroscopy of oils and extracts obtained from organic and conventional goji berries: yield, fatty acids, carotenoids and biological activities

“…The long-chain polyunsaturated fatty acids exhibited antibacterial activity against Propionibacterium acnes and S. aureus at the concentrations tested (32-1024 mg L À1 ) by Desbois & Lawlor (2013). Rostami et al (2016) reported that carotenoids extracted from Micrococcus roseus and Rhodotorula glutinis were able to inhibit S. enteritidis and E. coli.…”

Evaluation of Antimicrobial Activity and Identification of Yellow Pigmented Marine Sponge-Associated Fungi from Teluk Awur, Jepara, Central Java

“…The pigments displayed antimicrobial activity against MethicillinResistant Staphylococcus aureus (MRSA), Escherichia coli ATCC 25218 and Candida albicans. Another research reported that carotenoids pigment were able to inhibit Salmonella enteritidis (PTCC 1709) and E. coli (PTCC1260) (Rostami et al, 2016). In addition, crude extract of pigment from Streptomyces sp.…”