Solubility determination and correlation for o-phenylenediamine in (methanol, ethanol, acetonitrile and water) and their binary solvents from T= (283.15–318.15) K

Yao, Ganbing; Yao, Qingcang; Xia, Zhanxiang; Li, Zhihui

doi:10.1016/j.jct.2016.10.018

Cited by 52 publications

(37 citation statements)

References 18 publications

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“…This ordering is not strictly consistent with the polar order of the solvent (acetonitrile > ethanol > n -propanol > iso -propanol) . This inconsistency and the cosolvency phenomenon indicate that the solubility of CST is influenced by complex reasons such as the solute–solvent interaction, the solvent–solvent interaction, the polarities of the solute and the solvent, the formation of hydrogen bond, − and so on.…”

Section: Resultsmentioning

confidence: 96%

Solubility Measurement and Correlation of Ceftiofur Sodium Trihydrate in Four Binary Solvent Mixtures

Liu

et al. 2020

J. Chem. Eng. Data

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The solubility of ceftiofur sodium trihydrate (CST) in binary solvent mixtures of water + acetonitrile, water + ethanol, water + n-propanol, and water + iso-propanol at temperatures from 273.15 to 313.15 K (P = 0.1 MPa) was measured by a laser dynamic method. The experimental results show that the solubility is positively correlated with temperature. In the four binary solvent systems, the solubility value of CST initially increases first and then decreases with increasing organic solvent composition. The maximum solubility values occur in the molar content of organic solvent of about 0.5 for water + acetonitrile, 0.5 for water + ethanol, 0.4 for water + npropanol, and 0.4 for water + iso-propanol. The accuracy of experimental results was examined by the Apelblat model, the Van't-JA model, and the Apel-JA model, and the Apelblat model shows the best fitting performance.

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Section: Resultsmentioning

confidence: 96%

Solubility Measurement and Correlation of Ceftiofur Sodium Trihydrate in Four Binary Solvent Mixtures

Liu

et al. 2020

J. Chem. Eng. Data

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“…Jouyban has reviewed the cosolvency models for solid solubility in a cosolvent mixture . Here, the Jouyban–Acree, ,, van’t Hoff–Jouyban–Acree, , and Apelblat–Jouyban–Acree models , are used in describing propylthiouracil solubility in aqueous cosolvent solutions of EG, NMP, DMF, and DMSO.…”

Section: Theoretical Considerationmentioning

confidence: 99%

“…This Jouyban–Acree model (eq ) presents a precise description of the dependence of solubility upon both solvent composition and temperature for binary mixtures. ,, here, x w , T refers to the mole fraction solubility of the solute in mixed solvents at T /K; w 1 and w 2 refer to the mass fractions of solvents 1 (namely EG, DMF, NMP, and DMSO) and 2 (namely water) in the absence of propylthiouracil, respectively; x 1, T and x 2, T stand for the solubility of propylthiouracil in mole fraction in pure solvents. The model parameters are denoted J i .…”

Section: Theoretical Considerationmentioning

confidence: 99%

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Propylthiouracil Solubility in Aqueous Solutions of Ethylene Glycol, N,N-Dimethylformamide, N-Methyl-2-pyrrolidone, and Dimethylsulfoxide: Measurement and Thermodynamic Modeling

Yin

Zhao

2019

J. Chem. Eng. Data

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Solubility values of propylthiouracil dissolved in four neat solvents of N,N-dimethylformamide (DMF), N-methyl-2-pyrrolidone (NMP), dimethylsulfoxide (DMSO), and ethylene glycol (EG) and aqueous cosolvent solutions of DMF, NMP, EG, and DMSO from 293.15 to 333.15 K were determined. The determination process was carried out using the saturation shake-flask method at 101.1 kPa. At the identical temperature and cosolvent composition of DMF, NMP, EG, or DMSO, the solubility of propylthiouracil in mole fraction was maximum in DMSO (DMF) (1) + water (2) systems, and minimum in EG (1) + water (2) systems. Through the van't Hoff−Jouyban−Acree, Jouyban−Acree, and Apelblat− Jouyban−Acree models, the solubility of propylthiouracil was correlated very well, acquiring root-mean-square deviation values that are smaller than 9.75 × 10 −4 and relative average deviation values that are smaller than 3.01%.

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“…Moreover, aqueous mixtures of methanol have been analyzed in studies of cosolvency and/or preferential solvation of some drugs and drug-like compounds as compiled in the literature [10]. Furthermore, the solubility of some other compounds in these mixtures have been studied more recently [11][12][13][14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Solubility, Dissolution Thermodynamics and Preferential Solvation of Meloxicam in (Methanol + Water) Mixtures

et al. 2021

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Solubility of meloxicam in {methanol + water} mixtures from 293.15 to 313.15 K has been determined and correlated by means of the Jouyban-Acree model. By using the van't Hoff and Gibbs equations the respective apparent thermodynamic quantities for the dissolution and mixing processes, namely Gibbs energy, enthalpy, and entropy, were calculated. A non-linear enthalpy-entropy relationship was observed in the plot of enthalpy vs. Gibbs energy exhibiting negative but variable slopes in the composition region 0.00 < x 1 < 0.60 and variable negative and positive slopes in the other mixtures. Based on the inverse Kirkwood-Buff integrals it follows that meloxicam is preferentially solvated by water molecules in water-rich mixtures but preferentially solvated by methanol molecules in mixtures 0.31 < x 1 < 1.00.

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Solubility determination and correlation for o-phenylenediamine in (methanol, ethanol, acetonitrile and water) and their binary solvents from T= (283.15–318.15) K

Cited by 52 publications

References 18 publications

Solubility Measurement and Correlation of Ceftiofur Sodium Trihydrate in Four Binary Solvent Mixtures

Solubility Measurement and Correlation of Ceftiofur Sodium Trihydrate in Four Binary Solvent Mixtures

Propylthiouracil Solubility in Aqueous Solutions of Ethylene Glycol, N,N-Dimethylformamide, N-Methyl-2-pyrrolidone, and Dimethylsulfoxide: Measurement and Thermodynamic Modeling

Solubility, Dissolution Thermodynamics and Preferential Solvation of Meloxicam in (Methanol + Water) Mixtures

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