The solubility of 3-bromo-4-hydroxybenzaldehyde in 16
monosolvents
of n-pentanol, methanol, isobutanol, ethanol, ethylene
glycol (EG), n-propanol, acetonitrile, isopropanol, N,N-dimethylformamide (DMF), n-butanol, n-octanol, cyclohexane, water, ethyl acetate,
dimethylsulfoxide (DMSO), and 1,4-dioxane was attained through experiment
via the saturation shake-flask method covering from 278.15 K to 323.15
K under local ambient pressure p = 101.2 kPa. The
solubility magnitude in mole fraction of 3-bromo-4-hydroxybenzaldehyde
in the selected solvents raised as the studied temperature raised
and had the subsequent order in various monosolvents: (n-octanol, DMF) > 1,4-dioxane > (DMSO, n-pentanol)
> n-butanol > isobutanol > ethyl acetate
> n-propanol > isopropanol > ethanol >
acetonitrile > EG >
methanol > cyclohexane > water. The interactions of solvent–solute
and solvent–solvent molecules were inspected by using a method
of linear solvation energy relationships. The NRTL model, λh equation, modified Apelblat equation, and Wilson model
were employed herein to mathematically correlate the solubility data.
The results specified that the gained maximum relative average deviation
(RAD) and root-mean-square deviation (RMSD) values through these models/equations
were, respectively, 2.86 × 10–2 and 942.9 ×
10–6. The RAD values were lower obtained through
the modified Apelblat equation than the other equations/models for
a given solvent. As well, the mixing properties of dissolution, activity
coefficient at infinitesimal concentration, and reduced excess enthalpy
were calculated based on the Wilson equation.