Solitary Neurogenous Sarcomas of the Head and Neck

DeFries, Capt Hugh O.; Nolph, Michael B.; Kornblut, Alan D.

doi:10.1177/019459987908700111

Cited by 9 publications

(3 citation statements)

References 15 publications

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“…These tu mors spread hematogenously; therefore, a regional lymphadenectomy is not warranted. Augmentation with postoperative radiation therapy appears to decrease re currence rates, 9 whereas chemotherapy is reserved for unresectable or metastatic lesions. 2 These tumors have a relatively poor prognosis, with a 5-year survival rate between 50% and 65%.…”

Section: Discussionmentioning

confidence: 99%

Recurrent Neurogenic Sarcoma of the Paranasal Sinuses

Costantino¹,

Friedman²,

Karlan³

et al. 1990

Otolaryngol.--head neck surg.

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Section: Discussionmentioning

confidence: 99%

Recurrent Neurogenic Sarcoma of the Paranasal Sinuses

Costantino¹,

Friedman²,

Karlan³

et al. 1990

Otolaryngol.--head neck surg.

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“…Solitary tumors are more prone to recognition than those associated with neurofibromatosis because the histologic appearance resembles that of other sarcomas and sometimes undifferentiated carcinomas 2 . Electron microscopy or immunohistochemical studies are needed to confirm the diagnosis of malignant schwannomas 3 . The presentation and management of an extremely rare case of malignant schwannoma in the thyroid gland is reported.…”

mentioning

confidence: 99%

“…2 Electron microscopy or immunohistochemical studies are needed to confirm the diagnosis of malignant schwannomas. 3 The presentation and management of an extremely rare case of malignant schwannoma in the thyroid gland is reported.…”

mentioning

confidence: 99%

Malignant schwannoma of the thyroid gland

Alghamdi

Fageeh

Dewan

2000

Otolaryngol.--head neck surg.

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Most malignant schwannoma are deeply situated, and some may arise from superficial neurofibromas. 1 Solitary tumors are more prone to recognition than those associated with neurofibromatosis because the histologic appearance resembles that of other sarcomas and sometimes undifferentiated carcinomas. 2 Electron microscopy or immunohistochemical studies are needed to confirm the diagnosis of malignant schwannomas. 3 The presentation and management of an extremely rare case of malignant schwannoma in the thyroid gland is reported.

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Nonepithelial tumors of the nasal cavity, paranasal sinuses and nasopharynx. A clinicopathologic study. XII: Schwann cell tumors (neurilemoma, neurofibroma, malignant schwannoma)

Perzin

Panyu

Wechter

1982

Cancer

109

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Twelve Schwann cell tumors (two neurilemomas, six neurofibromas, and four malignant schwannomas), arising in the nasal cavity, paranasal sinuses or nasopharynx, are described. Schwann cell neoplasms only rarely develop in this area. Clinically, these tumors lead to nonspecific symptoms including nasal obstruction, epistaxis, facial pain and swelling, and proptosis, similar to those produced by other neoplasms that involve this area. On radiologic examination, a mass lesion may be identified. Benign Schwann cell tumors may lead to bone erosion, which thus is not necessarily a sign of malignancy. The correct diagnosis of Schwann cell tumor is usually made only when histologic sections are studied. The histologic differentiation between Schwann cell neoplasms and myxomas, fibroblastic tumors, fibrous histiocytomas and fibro‐osseous lesions is discussed. Treatment depends upon the type of tumor. Neurilemomas, which usually are encapsulated neoplasms, can be treated by local excision. Neurofibromas may infiltrate extensively, and thus may require an extensive surgical resection; however, functional and cosmetic considerations should be taken into account because neurofibromas, even if incompletely excised, may recur clinically only after many years. Malignant schwannomas tend to be aggressive neoplasms, but because of the anatomy of the area, radical resections leading to complete removal of the tumor cannot always be carried out.

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Solitary Neurogenous Sarcomas of the Head and Neck

Cited by 9 publications

References 15 publications

Recurrent Neurogenic Sarcoma of the Paranasal Sinuses

Recurrent Neurogenic Sarcoma of the Paranasal Sinuses

Malignant schwannoma of the thyroid gland

Nonepithelial tumors of the nasal cavity, paranasal sinuses and nasopharynx. A clinicopathologic study. XII: Schwann cell tumors (neurilemoma, neurofibroma, malignant schwannoma)

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