Background
To review the Shamblin classification of carotid body paragangliomas (CBPs) and the role of intra‐arterial stenting in their surgical management.
Methods
Retrospective case series of 20 patients with 28 CBPs that were surgically resected at our center. Intra‐arterial stenting was performed in Shamblin II and II classes.
Results
The mean follow‐up was 47.8 months. Five (17.9%) tumors were Shamblin class I, 15 (53.6%) were class II, and 8 (28.6%) were class III. Thirteen (68.4%) CBPs were associated with other paragangliomas. The internal carotid artery (ICA) was stented preoperatively in eight (28.6%) cases and occluded in four (14.3%) cases. The tumor extended to the jugular foramen in six cases (21.4%). Intraoperatively, there was an ICA injury in one case of Shamblin II CBP in the present era.
Conclusions
The proposed classification enables the clinician to plan the management of the ICA and the right approach. Stenting of the ICA gives a chance for complete tumor removal with arterial preservation.
255supernumerary teeth, and delayed eruption of permanent teeth; the mother had a similar clinical history. The RUNX2 mutation analysis revealed a frameshift mutation caused by a cytosine deletion at nucleotide 1205 in exon 8 (c.1205delC) in both subjects. Conclusion: We found one case of a c.1205delC mutation in an extensive literature search, but the clinical condition of the patient was not described. Therefore, we were unable to compare the clinical presentations associated with this mutation. However, we believe this report provides a useful basis for genotypic and phenotypic analyses in cleidocranial dysplasia. http://dx.
This study looks at the incidence of head and neck cancer in the Southwest Region of the Kingdom of Saudi Arabia (Asir Region). There were a total of 204 newly diagnosed patients seen at Asir Central Hospital between 1987 and 1992; 113 males and 91 females. All were Saudi patients. Frequency at various sites with reference to sex and age was determined and comparison with local and international published reports was made. To the best of our knowledge, this is the first paper in the Kingdom to look at head and neck cancer as a distinct entity. In this study, skin cancer was the most common among males followed by oral and pharyngeal cancers. Among females, thyroid cancer was the most common followed by skin and oral cancers. Some preventive measures are discussed. Ann Saudi Med 1994;14(5):383-386. Two studies reviewed from different parts of the Kingdom that looked at the whole body cancers estimated the incidence of head and neck cancers to be 18.4% and 12.2%. 2,3 In another study from the Eastern Province, the number was 4.5% excluding skin and thyroid cancers. 4 The authors of the first two papers stated that the head and neck cancers are more common in this country compared to western countries. This assertion is borne out in our study. This is a hospital-based study of the pattern of head and neck cancers presenting to a 576 bed tertiary care facility. This represents 21.4% of total hospital beds available in the region (2687).
Material and MethodsThis is a retrospective study based on data collected from the charts of 204 patients of all age groups, diagnosed and in most instances treated at Asir Central Hospital over a period of six years (January 1987 to December 1992). This represents 0.79% of the total admissions (52,768) during the study period. Carcinomas in situ were excluded. Non-Saudi patients were also excluded. Metastasis from sites other than the head and neck region were not included. Only patients with confirmed histological diagnosis were included in this study. The data obtained was compared with data previously reported from other institutions regarding relative frequency, the rank orders, and histological types.
ResultsTwo hundred and four patients form the basis of this study; 55.3% were males. Only Saudi patients were included in this study. Their ages ranged from three to 91 years with an average age of 57 for males and 52 for females. Cancers of the skin, thyroid, oral cavity, pharynx and lymphoreticular system were the most commonly encountered. Figure 1 shows a map of Saudi Arabia showing the location of Asir Region. Figure 2 shows the ages and sex distribution of head and neck cancers. The total population of the Asir Region is approximately 1,500,000 according to the last census done six months ago and the number of all cases of cancer in Asir at the time of this study were 1322. Fifteen and four-tenths percent were head and neck cancers reducing to 9.6% when thyroid and skin cancers are excluded. The incidence per 100,000/year is approximately 16.6 for all body cancers and 2.72 ...
To evaluate the accuracy and efficacy of fine-needle aspiration cytology (FNAC) in diagnosing thyroid nodules, correlating it with the histopathological findings. Methods: A retrospective evaluation of 314 patients was undertaken at a tertiary referral center of King Abdullah Medical City (KAMC), Makkah, Kingdom of Saudi Arabia, between 2010-2019. Patients who presented with thyroid swellings underwent ultrasonography and FNAC. If indicated, surgery was performed. The FNAC findings were compared to the final histopathological reports. Results: The findings for FNAC from our data set of 314 patients showed a sensitivity value of 79.8%, Original Article specificity of 82.1%, accuracy of 74.8%, positive predictive value of 74.8%, and negative predictive value of 85.9%. Conclusion: Our study showed that FNAC has high sensitivity and specificity in the initial evaluation of patients with thyroid nodules. When guided by ultrasonography, the accuracy can be markedly improved. Molecular markers once widely available can improve the diagnostic power of FNAC to be no less than the histopathologic evaluation of thyroid tissue.
PURPOSE:
The primary goal of this study is to analyze the reasons why refractive surgery was not performed for candidates who requested the procedure among single eye-clinic visitors in Saudi Arabia. Secondarily, we aimed to determine the corneal parameters that are characteristic of Saudi population and to figure out the relationship between the magnitude of central corneal thickness and the degree of myopia.
METHODS:
A retrospective data was collected for all patients who presented to a single-surgeon eye clinic at King Abdul Aziz Medical City-National Guard, Saudi Arabia, seeking refractive surgery between January 2010 and December 2015.
RESULTS:
Unstable refraction (21.78%) followed by amblyopia with unrealistic expectations (18.75%) and high myopia (15.62%) were the most common reasons not to proceed with refractive surgery in the included sample. The mean central corneal thickness for all patients included in this study was (538 μm ± 32.6). We found no significant relationship between central corneal thickness and the degree of myopia OD [rs(178) = −0.017,
P
= 0.823] and OS [rs(182) = 0.016,
P
= 0.831] for right and left eyes, respectively.
CONCLUSION:
Unstable refraction followed by amblyopia with unrealistic expectations and high myopia were the leading causes not to perform refractive surgery in this study. No significant relationship can be figured out between central corneal thickness and the degree of myopia.
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