255supernumerary teeth, and delayed eruption of permanent teeth; the mother had a similar clinical history. The RUNX2 mutation analysis revealed a frameshift mutation caused by a cytosine deletion at nucleotide 1205 in exon 8 (c.1205delC) in both subjects. Conclusion: We found one case of a c.1205delC mutation in an extensive literature search, but the clinical condition of the patient was not described. Therefore, we were unable to compare the clinical presentations associated with this mutation. However, we believe this report provides a useful basis for genotypic and phenotypic analyses in cleidocranial dysplasia. http://dx.

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