Solid-State Double Nuclear Magnetic Resonance Study of the Local Structure of Calcium Phosphate Nanoparticles Synthesized by a Wet-Mechanochemical Reaction

Isobe, Tetsuhiko; Nakamura, Satoshi; Nemoto, Rei; Senna, Mamoru; Sfihi, H.

doi:10.1021/jp0138936

Cited by 82 publications

(97 citation statements)

References 19 publications

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“…Only one asymmetric peak is observed. Its maximum is slightly shifted compared to non-substituted HA (2.6 ppm vs 2.8 ppm), [80] and the signal is ~1 ppm broader at half maximum, with a tailing towards high frequencies. These observations show that there is a larger variety of environments around the phosphates in Mg-HA, which can be due to the presence of Mg 2+ cations occupying different neighbouring positions (see Figure 2), and also to the structural distortions of the HA lattice which can induce slight rotations of the phosphate groups and small variations in the P-O bond distances and O-P-O bond angles.…”

Section: Dft Calculations Of the Nmr Parametersmentioning

confidence: 89%

Magnesium incorporation into hydroxyapatite

Laurencin¹,

Almora‐Barrios²,

Leeuw³

et al. 2011

Biomaterials

308

190

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The incorporation of Mg in hydroxyapatite (HA) was investigated using multinuclear solid state NMR, X-ray absorption spectroscopy (XAS) and computational modeling. High magnetic field 43 Ca solid state NMR and Ca K-edge XAS of a ~10% Mg-substituted HA were performed, bringing direct evidence of the preferential substitution of Mg in the Ca(II) position. 1 H and 31 P solid state NMR show that the environment of the anions is disordered in this substituted apatite phase. Both Density Functional Theory (DFT) and interatomic potential computations of Mg-substituted HA structures are in agreement with these observations. Indeed, the incorporation of low levels of Mg in the Ca(II) site is found to be more favourable energetically, and the NMR parameters calculated from these optimized structures are consistent with the experimental data. Calculations provide direct insight in the structural modifications of the HA lattice, due to the strong contraction of the M•••O distances around Mg. Finally, extensive interatomic potential calculations also suggest that a local clustering of Mg within the HA lattice is likely to occur.

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Section: Dft Calculations Of the Nmr Parametersmentioning

confidence: 89%

Magnesium incorporation into hydroxyapatite

Laurencin¹,

Almora‐Barrios²,

Leeuw³

et al. 2011

Biomaterials

308

190

View full text Add to dashboard Cite

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“…In this respect, the possibility to turn quite smoothly the bulk structure from highly to poorly crystalline or actually disordered by changing preparation conditions, such as temperature, presence of anionic and/or cationic substituents, nucleation on collagen fibers, is well known [101]. Still, in recent years, several studies [102][103][104][105] revealed that HA nanoparticles can be coated by an amorphous, non-apatitic surface layer surrounding a crystalline hydroxyapatite bulk. However, the possibility of obtaining apatitic particles with crystalline structure extended up to the surface was recently reported [106].…”

Section: The Inorganic Bone Matrix: Hydroxyapatitementioning

confidence: 99%

Surface Treatments and Functional Coatings for Biocompatibility Improvement and Bacterial Adhesion Reduction in Dental Implantology

et al. 2016

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Surface modification of dental implants is a key process in the production of these medical devices, and especially titanium implants used in the dental practice are commonly subjected to surface modification processes before their clinical use. A wide range of treatments, such as sand blasting, acid etching, plasma etching, plasma spray deposition, sputtering deposition and cathodic arc deposition, have been studied over the years in order to improve the performance of dental implants. Improving or accelerating the osseointegration process is usually the main goal of these surface processes, but the improvement of biocompatibility and the prevention of bacterial adhesion are also of considerable importance. In this review, we report on the research of the recent years in the field of surface treatments and coatings deposition for the improvement of dental implants performance, with a main focus on the osseointegration acceleration, the reduction of bacterial adhesion and the improvement of biocompatibility.

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“…At about 190°C and 340°C, there are small and big peaks in the first derivative curve of the apatite obtained by calcination, these peaks accompanying weight losses of 0.4 and 0.9%, respectively. These losses might refer to the dehydration of ions HPO 4 − 2 according to the following reaction [44]:…”

Section: Thermal Gravimetric Analysismentioning

confidence: 99%

“…Therefore, different production methods were reported such as mechanochemistry [3,4], ultrasonic irradiation [5], microwave irradiation [6,7], sol-gel [8][9][10][11], chemical precipitation [12,13], hydrothermal method [14][15][16], hydrolysis [17], microemulsion [18][19][20], and emulsion liquid membrane [21]. The synthesized HAp does not have adequate biological properties as the natural apatite existing in bones.…”

Section: Introductionmentioning

confidence: 99%