Solid State Detectors in Behavioral Studies

In vivo measurement of 32P in the brain of a freely moving rat

“…The electronic system described earlier (Ewins et al, 1970) was used in these studies. The detector was modified slightly in order to reduce the dimension of the preamplifier container (Fig.…”

“…The detector was modified slightly in order to reduce the dimension of the preamplifier container (Fig. Ib) to 6 mm in diameter (instead of 10 mm as in the previously described detector, Ewins et al, 1970). A block diagram of the counting system is shown in Fig.…”

“…Rats were prepared by chronic cannulation of the aorta and the vena cava in the abdomen. Polyethylene tubes were led out of the animal in the neck area (Ewins et al, 1970). Two identical detectors were used; one was placed above the brain as described, and the second was placed above the blood flowing from the artery t o the vein.…”

“…One of the main advantages of this type of detector for measurements of radioactivity in living tissues is thekmall size of probe one can use, thereby minimizing both trauma and injury. In a previous article (Ewins et al, 1970), we described the construction of a new semiconductor which could be used for the measurement of 32P in the brain of small freely moving animals, such as large rodents, cats, or dogs.…”