Software to generate 3-D continuous printing paths for the fabrication of tissue engineering scaffolds

Dávila, José Luis; Freitas, Matheus Stoshy de; Neto, Paulo Inforçatti; Silveira, Zilda de Castro; Silva, Jorge Vicente Lopes da; d’Ávila, Marcos Akira

doi:10.1007/s00170-015-7866-8

Cited by 13 publications

(13 citation statements)

References 13 publications

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“…The 0°/90° architecture proposed for the scaffolds was obtained, which confirmed the compatibility between BioScaffold PG geometry generation software and 3D printer linked program, Fab@Home. Such an architecture is known to guarantee interconnectivity between pores, which is a determining geometric factor for the application of scaffolds in tissue engineering [11, 31]. The reproducibility factor, which consists in the manufacture of scaffolds with similar compliance, is observed mainly in Figures 2(a), 2(b), and 2(c) and related to the scaffolds with Biosilicate®.…”

Section: Resultsmentioning

confidence: 99%

“…As known, the higher the PH, the poor the layers bonding, therefore, an inadequate definition of the layer height can result in the detachment of the layers from the structure. On the other hand, the presence of flattening in the regions of union of one layer to another, caused by the lower PH in relation to the diameter of the extruded strand, is indicative of good bonding [31]. Figures 3(b)–3(d) show SEM images of the cross sections of the fabricated scaffolds of PCL with 1, 3, and 5 wt.% Biosilicate®, respectively.…”

Section: Resultsmentioning

confidence: 99%

“…They were compacted and exported to a file extension compatible with the operating/control system of the 3D printer, e.g. STL, G-Code.txt, or Points.txt [31]. The software monitors the entire manufacturing process of the scaffold and provides all processing information, such as expected time for production, data on a single screw-based head, and rotation speed of the X, Y coordinates [29, 30].…”

Section: Introductionmentioning

confidence: 99%

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Fabrication and Characterization of Scaffolds of Poly(ε-caprolactone)/Biosilicate® Biocomposites Prepared by Generative Manufacturing Process

Cunha

Neto

Micocci

et al. 2019

International Journal of Biomaterials

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Scaffolds of poly(ε-caprolactone) (PCL) and their biocomposites with 0, 1, 3, and 5 wt.% Biosilicate® were fabricated by the generative manufacturing process coupled with a vertical miniscrew extrusion head to application for restoration of bone tissue. Their morphological characterization indicated the designed 0°/90° architecture range of pore sizes and their interconnectivity is feasible for tissue engineering applications. Mechanical compression tests revealed an up to 57% increase in the stiffness of the scaffold structures with the addition of 1 to 5 wt.% Biosilicate® to the biocomposite. No toxicity was detected in the scaffolds tested by in vitro cell viability with MC3T3-E1 preosteoblast cell line. The results highlighted the potential application of scaffolds fabricated with poly(ε-caprolactone)/Biosilicate® to tissue engineering.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Fabrication and Characterization of Scaffolds of Poly(ε-caprolactone)/Biosilicate® Biocomposites Prepared by Generative Manufacturing Process

Cunha

Neto

Micocci

et al. 2019

International Journal of Biomaterials

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“…The uniform lattices with regular continuous patterns can be generated using BioScaffolds PG. It is a specific software for scaffold generation for bioprinting[ 92 ]. It has the necessary parameters for modeling of a customizable uniform scaffold and the opportunity to export the models for the Fab@Home platform[ 93 ].…”

Section: Software For Bioprintingmentioning

confidence: 99%

Software for Bioprinting

Pakhomova¹,

Popov²,

Maltsev³

et al. 2024

IJB

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The bioprinting of heterogeneous organs is a crucial issue. To reach the complexity of such organs, there is a need for highly specialized software that will meet all requirements such as accuracy, complexity, and others. The primary objective of this review is to consider various software tools that are used in bioprinting and to reveal their capabilities. The sub-objective was to consider different approaches for the model creation using these software tools. Related articles on this topic were analyzed. Software tools are classified based on control tools, general computer-aided design (CAD) tools, tools to convert medical data to CAD formats, and a few highly specialized research-project tools. Different geometry representations are considered, and their advantages and disadvantages are considered applicable to heterogeneous volume modeling and bioprinting. The primary factor for the analysis is suitability of the software for heterogeneous volume modeling and bioprinting or multimaterial three-dimensional printing due to the commonality of these technologies. A shortage of specialized suitable software tools is revealed. There is a need to develop a new application area such as computer science for bioprinting which can contribute significantly in future research work.

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“…elétrica; motor e controlador de temperatura, a Figura 14 mostra um esquema dimensionado da rosca de extrusão utilizada na Fab@CTI. O software utilizado para controlar a impressora foi o Fab@Home Model 1:V.0.24 RC6 [65] e o software utilizado para criar a geometria do scaffold foi o BioScaffolds PG[22].Os scaffolds foram projetados pelo software Bioscaffolds PG que permite definir as variáveis geométricas da amostra e gera os dados em arquivo compatível ao…”

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Fabricação de <i>scaffolds</i> de polímero reforçado para aplicação na bioengenharia tecidual

Barbosa¹

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Software to generate 3-D continuous printing paths for the fabrication of tissue engineering scaffolds

Cited by 13 publications

References 13 publications

Fabrication and Characterization of Scaffolds of Poly(ε-caprolactone)/Biosilicate® Biocomposites Prepared by Generative Manufacturing Process

Fabrication and Characterization of Scaffolds of Poly(ε-caprolactone)/Biosilicate® Biocomposites Prepared by Generative Manufacturing Process

Software for Bioprinting

Fabricação de <i>scaffolds</i> de polímero reforçado para aplicação na bioengenharia tecidual

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