Socio demographic and clinical profile of dengue fever cases at a tertiary care hospital, Hyderabad, Telangana

Abstract

Background: Dengue fever is caused by Dengue Virus, belonging to the family Flaviviridae, transmitted by Aedes aegypti and Aedes albopictus mosquito. There are four distinct dengue virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4). This viral disease of humans has become a major international public health concern in recent years. Differential diagnosis based on symptoms is challenging due to dengue’s non-specific symptoms such as fever, aches and fatigue that are often overlap with other endemic infections. Dengue-associated mortality can be reduced from 20–30% in severe cases to less than 1% with appropriate fluid replacement and supportive care, which is greatly facilitated by early diagnosis. Aim and objective: To study the demographic factors and clinical features of dengue fever cases in urban areas of Hyderabad.Methods: The present study was conducted by Department of Community Medicine in collaboration with Department of Microbiology, Kamineni academy of medical sciences and research center, Hyderabad. Study subjects: “Probable” dengue cases admitted in the various departments during July –December 2016. Data collection was done using a structured questionnaire. Serum samples were tested for NS1 antigen, IgM, IgG antibodies by rapid visual immunochromatography.Results: Out of 137 samples of clinically suspected dengue cases, 119 were found positive for dengue infection. Fever was the most common symptom found in all the patients Majority of cases, 56.3% were males. Thrombocytopenia, leucopenia and bleeding manifestation were found in 84.0 %, 84.8% and 58.8% patients respectively.Conclusions: Fever was the most common symptom found in all the patients. Majority of cases showed thrombocytopenia. Significant difference was found in the clinical signs and symptoms like fever, myalgia, hypotension, thrombocytopenia and leucopenia in dengue cases than controls.

Spatial Mapping the Dengue and Chikungunya Burden in a Rural Area near Bangalore- a Descriptive Cross-Sectional Study

“…Chajhlana SPS et al ( 17 ) and Dutta et al ( 18 ) had shown that more males were affected similar to the findings of the present study. In a study conducted by Balasubramaniam et al ( 19 ), fever was the most common symptom observed similar to the present study.…”

Frequency of dengue infection in febrile patients attended Dhaka Medical College Hospital during January to December, 2018

“…Most dengue patients detected during this study were males (68.6%), although male patients were also more likely to be enrolled in the study (69.3%). This difference likely arose from unequal health care utilization among male and female patients, which is a typical feature in South Asia 23 . The proportion of male febrile patients (38.52%), who were positive for dengue was similar to that of female febrile patients (39.85%), with the difference not being statistically significant (P > 0.05).…”

A clinico pathological profile of dengue fever in children in urban areas of Telangana

“…also P P Vazhayil et al, K Jayasree et al and Shubhankar Mishra et al and Anand et alstudies. 4,[6][7][8][9][10] In the present study most commonly affected age group is 6-10 years of age 95 cases (47.9%)(Table-2). K Jayasree et al study shows 6-10 yrs.…”

“…Study conducted by Anand et al found 83.3% positive cases. 4,5 Majority of cases are males 62% and 38% were females (Figure 1). Chajhlana SPS et al and Tabassum et al in their study found that there was more number of males.…”