Social cognition and Theory of Mind in patients with relapsing‐remitting multiple sclerosis

Bánáti, Miklós; Sándor, János; Mike, Andrea; Illes, Eniko; Bors, László; Feldmann, Ádám; Herold, Róbert; Illés, Zsolt

doi:10.1111/j.1468-1331.2009.02836.x

Cited by 108 publications

(120 citation statements)

References 52 publications

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“…However, differences in emotion recognition are discreet and subtle, and according to some researchers, correlate significantly with cognitive functioning, suggesting a global deficiency in the speed of information processing [50]. Despite some variability in findings, several contemporary studies support the thesis that ToM impairments are independent from neuropsychological functioning in adult patients with MS [49,56]. A correlation between impaired emotional perception and the physiological and social aspects of quality of life was found in MS [71].…”

Section: Social Cognition Impairments In Patients With Multiple Sclermentioning

confidence: 65%

“…A positive correlation was detected between duration of MS and level of empathy, that is, the greater the duration of the disease, the lower the empathy quotient [55,56,86]. Banati et al found profoundly increasing of the empathizing quotient (p 0.03) among patients with shortterm MS (n = 40) compared to controls (n = 35).…”

Section: Social Cognition Impairments Depending On Ms Durationmentioning

confidence: 99%

“…In 2010, Banati et al found more prominent ToM deficits in patients with longer disease duration (p = 0.05) [56]. In some research, the duration of the disease did not correlate with the emotional and cognitive scores from nonverbal tests [80], while Kraemer reported positive correlation between impaired social cognitive skills and executive function deficits in the early stages of the disease in fully ambulatory patients [6].…”

Section: Social Cognition Impairments In Patients With Multiple Sclermentioning

confidence: 99%

“…More errors of interpretation and lower total scores were reported in patients with MS when using nonverbal tests [56]. Subjects performed worse than controls (p < 0.05) at the facial symbol test (FST) [80].…”

Section: Social Cognition Impairments In Patients Withmentioning

confidence: 99%

“…A study of Banati et al registered a higher level of empathy, attributed by ambulatory MS subjects to themselves by using self-assessment questionnaire. The patients (n = 40) showed 14 times better empathizing abilities to themselves compared to control individuals (p < 0.05) [56]. Ot self-compassion mechanisms suppress anxiety and negative thinking [57].…”

Section: Social Cognition Impairments In Patients With Multiple Sclermentioning

confidence: 99%

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Social Cognition Impairments in Patients with Multiple Sclerosis and Comparison with Imaging Studies, Disease Duration and Grade of Disability

Ignatova¹,

Todorova²,

Surchev³

2016

Trending Topics in Multiple Sclerosis

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Cognitive impairments in multiple sclerosis (MS) are heterogeneous and their rate varies between 43% and 70%. A less studied aspect of cognition is social cognition, which is not a uniform theoretical construct. It includes emotion perception, prosody, empathy, theory of mind (ToM) and assessment of mood. In addition to progressive physical disability, social cognitive impairments are a reason for job loss in 24-80% of patients with MS, increased divorce rate, dissolution of partnerships and social communication difficulties.Social cognitive impairments are the result of disruptions in the mentalization network at the neuroanatomical, neurochemical and/or genetic level, which can lead to malfunctions in the dopaminergic-serotoninergic system and to compromising the development of neuroanatomical targets within the network. The wide dissemination of demyelinating lesions and cortical thinning typical of patients with MS often lead to anatomic and functional disorders of the above-mentioned specific brain structures. A correlation has been established among specific cortical areas involved in emotion identification from facial expression (right and left fusiform face area, frontal eye), emotion processing (right entorhinal cortex) and socially relevant information (left temporal pole). The most active brain region involved in social cognitive processing is the medal frontal cortex (MFC), which is described as the brain's social cognitive center. During performance of various sociocognitive tasks for mental state attribution, common areas of increased activation in the medial prefrontal gyrus and the temporoparietal junctions are registered bilaterally, while the area of the medial prefrontal cortex (the paracingulate cortex) is the only region uniquely activated by the performance of ToM.Most MRI studies of patients with MS found a correlation between the cognitive and/or affective disorders, on the one hand, and lesion localization, total lesion load, or cerebral atrophy, on the other. A significant correlation was also reported between © 2016 The Author(s). Licensee InTech. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.abnormal activities in specific cortical zones on fMRI, on the one hand, and clinical manifestation, conventional MRI findings and behavioral changes, on the other. Altered patterns of brain activity were found in all clinical phenotypes of MS, including when cognitive abilities were intact and/or restored, social cognitive dysfunction in MS actually affects all stages of the disease and all types of clinical course. The cortical plastic changes are a dynamic phenomenon that can be modulated by external factors. This phenomenon would facilitate the mapping of individual strategies for adequate treatment and rehabilitation of each patient.

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Section: Social Cognition Impairments In Patients With Multiple Sclermentioning

confidence: 65%

Section: Social Cognition Impairments Depending On Ms Durationmentioning

confidence: 99%

Section: Social Cognition Impairments In Patients With Multiple Sclermentioning

confidence: 99%

Section: Social Cognition Impairments In Patients Withmentioning

confidence: 99%

Section: Social Cognition Impairments In Patients With Multiple Sclermentioning

confidence: 99%

See 3 more Smart Citations

Social Cognition Impairments in Patients with Multiple Sclerosis and Comparison with Imaging Studies, Disease Duration and Grade of Disability

Ignatova¹,

Todorova²,

Surchev³

2016

Trending Topics in Multiple Sclerosis

View full text Add to dashboard Cite

show abstract

Testing social cognition in multiple sclerosis: Difference between emotion recognition and theory of mind and its influence on quality of life

et al. 2020

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Multiple Sclerosis

Carotenuto

Iodice

Arcara

2021

Handbook of Pragmatic Language Disorders

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Social cognition and Theory of Mind in patients with relapsing‐remitting multiple sclerosis

Abstract: In the absence of marked cognitive decline and disability, patients with ambulatory MS had a deficit interpreting social situations and performing in interpersonal contexts.

Cited by 108 publications

References 52 publications

Social Cognition Impairments in Patients with Multiple Sclerosis and Comparison with Imaging Studies, Disease Duration and Grade of Disability

Social Cognition Impairments in Patients with Multiple Sclerosis and Comparison with Imaging Studies, Disease Duration and Grade of Disability

Testing social cognition in multiple sclerosis: Difference between emotion recognition and theory of mind and its influence on quality of life

Multiple Sclerosis

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