Multiple Sclerosis

Carotenuto, Antonio; Iodice, Rosa; Arcara, Giorgio

doi:10.1007/978-3-030-74985-9_16

Cited by 1 publication

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“…In addition, earlier studies reported that MS patients have difficulties in understanding ambiguous sentences and metaphors ( Lethlean and Murdoch, 1997 ) and that they have impaired language production, specifically regarding flexibility in complex discourse; these difficulties were found to be related to cognitive impairment, particularly to executive dysfunction ( Arrondo et al, 2010 ), in line with the most recent data ( Carotenuto et al, 2018a ). Despite the limited number of studies, evidence points to a relevant deficit of pragmatics in MS ( Carotenuto et al, 2021 ), and to an association between pragmatic deficits and other cognitive abilities, especially executive functions.…”

Section: Introductionmentioning

confidence: 99%

Case report: Pragmatic impairment in multiple sclerosis after worsening of clinical symptoms

et al. 2022

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Pragmatics, defined as the ability to integrate language and context to communicate effectively, may be impaired in Multiple Sclerosis (MS). We present the case of a patient with active secondary progressive MS who, after a first neuropsychological assessment that evidenced only a slight pragmatic impairment, suffered a sudden worsening of her clinical conditions, treated with corticosteroids. After this clinical worsening, her pragmatic abilities declined markedly, both in comprehension and production. This worsening was accompanied by a decline only in one attention task, in the context of an overall stable cognitive functioning. We conclude that pragmatics may be a domain particularly susceptible to cognitive worsening, highlighting the importance of its assessment in clinical practice.

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Section: Introductionmentioning

confidence: 99%