Skeletal Muscle Stem Cells

LaBarge, Mark A.; Blau, Helen M.

doi:10.1016/b978-0-12-374729-7.00030-5

Cited by 3 publications

(1 citation statement)

References 234 publications

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“…Theoretically, a stem cell niche is composed of the stem cells themselves along with stromal support cells, extra cellular matrix proteins, blood vessels and neural inputs. The interaction between biomaterial and stem cells is described in the literature [27][28][29][30][31][32][33].…”

Section: Introductionmentioning

confidence: 99%

Biomimmetic surfaces effectively inhibiting coagulation process dedicated for cardiovascular devices

Major¹

2016

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Biomimmetic surfaces effectively inhibiting coagulation process dedicated for cardiovascular devicesThe work focused on developing coatings with niche-like surfaces that resemble stem cells. Structures similar to stem cell niches were designed to inhibit the fast division process and subsequently to influence the efficient endothelialisation. Using a plasma method, the surface topography and stiffness, as well as the microstructure, were modified by controlled residual stresses. The cells exhibited a potential for formation of the appropriate endothelial layer. Residual stresses affected the formation of the surface topography in a form of nano-wrinkles similar to niches in the tissue environment where stem cells are stored. Carbon-based films were deposited on reference substrates using a magnetron sputtering technique. Amorphous carbon and diamond like carbon with anode laser source were studied in the work. Niche-like structures were designed to catch stem cells from blood flow and prevent their rapid differentiation. The blood-material interaction under dynamic conditions was performed and described. Blood from above the analysed surface was collected after the test, and the quality of the blood was assessed along with the type of cellular response to the surface. The potential for endothelialisation was adjusted using human umbilical vein endothelium cells. The contact angle measurement was performed giving initial output information for tests on blood. The biomimetic approach considered nichelike structures reconstruction using materials science. In the work we have developed coatings that could mobilize and influence the differentiation of vascular endothelial cells.

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Section: Introductionmentioning

confidence: 99%

Biomimmetic surfaces effectively inhibiting coagulation process dedicated for cardiovascular devices

Major¹

2016

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Effects of the surface modification of polyurethane substrates on genotoxicity and blood activation processes

Major

Plutecka

Gruszczynska³

et al. 2017

Materials Science and Engineering: C

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The influence of surface topography elaborated by prism optics based laser interference modification on cell differentiation

Czyż

Marczak

Major

et al. 2016

MATERIAL ENGINEERING

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The direct laser interference lithography, based on bi-prism, tetragonal pyramid and an axicon was used as a tool for periodical structuring of different bioscaffolds. The simple, source laser system with stable Nd:YAG laser resonator, amplifying system (energy up to 1 J) and prism-based interferometer optics gave possibility to create periodical, linear, dotted and even circular surface structures, with high degree of periods, width and depth control. The general idea consists of the imitation of the structure and function of tissues and adoption of these solutions for the material science. It is well known that the influence of the artificial material on the cellular processes related to the differentiation, proliferation and growth are dependent on the chemical composition and surface topography as well as mechanical properties of applied materials. The most recent studies focus on the cell interaction with flat scaffolds. However, cells are found covering a highly rough surface in the blood vessels. The work was related to reconstruction of the structure and function and topography of luminal side of the blood vessels. The most important aspect was to recreate cellular niches which plays specific function on the activation and differentiation of stem cells. The mechanical stresses generated at any certain site depend on the surface micropatterns of the material as well as the other signals that cell receives from chemical stimuli. This work is one of the first attempts to determine correlation of surface micro-topography with biochemical stimulation by adsorbed on the materials surface molecules and both factors potential influence on cellular response. The study was aimed at showing the mechanism of human endothelial progenitor cells adhesion, morphology and function control in response to surface patterning. It was found that micro-channels enhanced intercellular connections forming tight junctions and the appropriate progenitor cell differentiation.

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Skeletal Muscle Stem Cells

Cited by 3 publications

References 234 publications

Biomimmetic surfaces effectively inhibiting coagulation process dedicated for cardiovascular devices

Biomimmetic surfaces effectively inhibiting coagulation process dedicated for cardiovascular devices

Effects of the surface modification of polyurethane substrates on genotoxicity and blood activation processes

The influence of surface topography elaborated by prism optics based laser interference modification on cell differentiation

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