Síndrome de boca ardiente: Eficacia de la aplicación tópica de capsaicina. Estudio piloto

Espinosa, S. León; Jornet, Pía López; Ros, R. Frutos

doi:10.4321/s0213-12852004000600004

Cited by 6 publications

(22 citation statements)

References 12 publications

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“…Such a result is in agreement with the reviewed literature on BMS, and with the involvement of other structures to a lower degree (2)(3)(4)6) . The xerostomia group mentioned a larger amount of structures affected with dry mouth, including the lips and the oropharynx (16,21,22) .…”

Section: Discussionsupporting

confidence: 81%

“…This datum may point that both BMS and dry mouth seem to affect mainly the population aged 50 years or around (1,15,24) . Regarding patients' clinical history, the symptomatic groups showed similarities in may aspects, which agrees with the reviewed literature (2,(4)(5)(6)(7)(8)11,16,22,23) . Some studies, however, found variations especially regarding the intensity of the symptom (4,22,24) .…”

Section: Discussionsupporting

confidence: 77%

“…This study confirmed the use of strategies to minimize the symptoms (6,11,19,23) , which shows that the subjects seek relief machanisms as a way to minimizing the symptomatology.…”

Section: Discussionsupporting

confidence: 59%

“…The intensity of the burning or blazing sensation is variable, and is intensified in the course of the day (4,6) . Frequently, the blazing sensation affects more than one area (2,4) , and the tongue is mentioned as the most affected structure (2)(3)(4)(5)(6)(7) ; it can also affect other structures of the oral cavity, such as lips, palate, gums and buccal mucosa (3)(4)(5) , as well as -though less frequently -the floor of the mouth (3) and the oropharynx (2) . The term "syndrome" in BMS is used because of the simultaneous association between the burning sensation and other subjective symptoms, such as xerostomia and dysgeusia (2,4,7,8) .…”

Section: Introductionmentioning

confidence: 99%

“…Complaints about the oral functions are so described: aggravation of the symptomatology when speaking and ingesting hot food (9) , as well as acid (10) and spicy (7,11) foods; improvement or suppression of the symptom in liquid and food intake (6,11) ; relief of the sympom when ingesting cold foods (10) . Subjects also report that the ingestion of liquid or food at extreme temperatures may either aggravate or alleviate the symptoms (2) .…”

Section: Introductionmentioning

confidence: 99%

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Queixas fonoaudiológicas e verificação da fala de indivíduos com diagnóstico de ardência bucal e xerostomia

Pastana

Cantisano

Bianchini³

2013

Audiol., Commun. Res.

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OBJETIVO: Investigar as queixas das funções orais em presença dos sintomas de ardência e secura bucal e analisar as alterações da fala em seu aspecto articulatório. MÉTODOS: Foram avaliados 66 indivíduos com idade entre 30 e 78 anos, divididos em três grupos: grupo ardência bucal, grupo xerostomia e grupo sem sintomas bucais. Foram realizadas entrevistas, exame clínico da cavidade oral e gravação da fala, com utilização de fichário evocativo. RESULTADOS: A característica comum nos dois primeiros grupos foi a presença do sintoma de secura bucal. Na localização dos sintomas, o grupo xerostomia apresentou maior quantidade de estruturas afetadas pelo sintoma. As queixas mais referidas por esse grupo foram cansaço e força na fala e força e engasgos à deglutição. A queixa de força foi significativa, na comparação com grupo de ardência bucal, com aumento do sintoma provocado pela função de fala. Dos sujeitos que se queixaram de boca seca, como sintoma principal, ou associado, a maioria apresentou ruídos durante a fala. O grupo xerostomia apresentou maior ocorrência desse ruído. Não foram evidenciadas alterações fonéticas nos grupos de sintomas bucais. CONCLUSÃO: Das queixas envolvendo as funções orais, falar e deglutir com força foram as mais referidas pelos indivíduos do grupo xerostomia. Observou-se a presença de estalidos na fala da maioria dos sujeitos com o sintoma de secura bucal. Apesar das sintomatologias apresentadas e do número de estruturas orais afetadas, não houve evidência de alteração fonética nos indivíduos com sintomas bucais.

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Section: Discussionsupporting

confidence: 81%

Section: Discussionsupporting

confidence: 77%

“…This study confirmed the use of strategies to minimize the symptoms (6,11,19,23) , which shows that the subjects seek relief machanisms as a way to minimizing the symptomatology.…”

Section: Discussionsupporting

confidence: 59%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Queixas fonoaudiológicas e verificação da fala de indivíduos com diagnóstico de ardência bucal e xerostomia

Pastana

Cantisano

Bianchini³

2013

Audiol., Commun. Res.

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Aetiology and therapeutics of burning mouth syndrome: an update

et al. 2012

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Aetiology and therapeutics of burning mouth syndrome: an updateObjective: To provide a review on the aetiology and therapeutic options for the management of patients with burning mouth syndrome (BMS). Background: BMS is a chronic disorder that frequently affects women and is characterised by burning symptoms of the oral mucosa without clinical signs. This syndrome has a complex and multifactorial characteristics, but its aetiology remains unknown and this makes it difficult with regard to the treatment and management of such patients. Despite not being accompanied by evident organic changes and not presenting risks to health, BMS can significantly reduce the quality of life for patients. Methods and materials: The article reviews the literature regarding aetiologic factors, clinical implications and treatment of BMS. Conclusion: The involvement of neurological, emotional and hormonal alterations is proposed in BMS aetiology. However the mechanisms of its development are complex and not completely understood. Tricyclic antidepressants, benzodiazepines and antipsychotic drugs are the most accepted options in treatment and show variable results. The correct diagnosis of BMS and the exclusion of possible local or systemic factors that can be associated with the symptoms are fundamental. It is also important to evaluate the quality of life for these patients to recognise the potential impact of this condition on their lives.

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Estudo clínico da atividade da capsaicina em portadores da Síndrome de Ardência Bucal

Fréo¹

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Burning mouth syndrome (BMS) is characterized by an oral burning sensation, with no corresponding clinical signs or laboratory abnormalities. The etiology is unknown, and there was no satisfactory treatment available. The objective of this study was to evaluate the effectiveness of topical use of capsaicin, as an alternative therapy in a group of BMS patients, as well as to correlate anxiety and depression levels to response to the therapy applied. Twenty BMS individuals in accordance to the terms to informed consent comprised the study group. Fifteen subjects were allocated to the test group (TG) and were treated with capsaicin, in daily applications for three weeks, one-week interval and an additional treatment cycle of four weeks. The control group (CG) was treated with the cream base used as a vehicle of capsaicin preparation, during the same period. All patients were examined 30 days after discontinuation of the medication. Results were assessed through a visual analogue scale (VAS) and a questionnaire on the global perceived effect (GPE). The average symptoms intensity before treatment, on EVS, was 5.1 (TG) and 4.4 (CG). At the fourth week control, TG presented reduction on the level of symptoms (EVS = 3.6), while CG presented an increase of symptoms intensity (VAS = 4.8). In the TG, between fourth and eighth week of follow-up, symptoms decreased around 8.3%, and between the eighth and twelfth week there was an increase of 13.5% on symptoms intensity. In the CG it was registered 22.8% of worsening (EVS = 5.75) between the beginning of the study and the twelfth week of control. On GPE assessment, six patients (40%) of TG and one patient of CG (20%), presented some relief of symptoms; four patients TG (26.6%) reported total remission of symptoms after treatment with capsaicin and one patient (20%) of control; three patients of TG and two of the CG remained unaltered. There were reports of worsening in two patients (13.3%) of TG and one (20%) of the CG. Eight patients of TG showed a high level of anxiety and seven moderate levels. In CG one patient presented low level, three showed a moderate level and one was ranked as having a high level of anxiety. CES-D suggested traits of depression in ten patients (66.6%) of TG and 40% (2) of the CG. We concluded that capsaicin is effective in controlling the burning symptom of BMS, suggesting some correlation with initial symptoms intensity and the maintenance of drug use. Moreover, there was some correspondence between high levels of anxiety and traits of depression, but it was not perceived influence of these aspects to the therapeutic response.

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Síndrome de boca ardiente: Eficacia de la aplicación tópica de capsaicina. Estudio piloto

Cited by 6 publications

References 12 publications

Queixas fonoaudiológicas e verificação da fala de indivíduos com diagnóstico de ardência bucal e xerostomia

Queixas fonoaudiológicas e verificação da fala de indivíduos com diagnóstico de ardência bucal e xerostomia

Aetiology and therapeutics of burning mouth syndrome: an update

Estudo clínico da atividade da capsaicina em portadores da Síndrome de Ardência Bucal

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