Simultaneous Measurements of the Blood Volume in Man and Dog by Means of Evans Blue Dye, T1824, and by Means of Carbon Monoxide. I. Normal Subjects 1

Hopper, James; Tabor, Herbert; Winkler, Alexander W.

doi:10.1172/jci101533

Cited by 54 publications

(27 citation statements)

References 18 publications

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“…Similar results with the Evans Blue and carbon-monoxide methods have also been obtained in the same normal subjects (25,26).…”

Section: Plasma Proteinssupporting

confidence: 84%

Blood and Extracellular Fluid Studies in Chronic Malnutrition in Infancy 12

Gollan¹

1948

J. Clin. Invest.

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One problem facing the Italian Medical Nutrition Mission in 1945-46 was the great number of infants and children suffering from severe and chronic malnutrition. Through lack of sanitation, milk control and proper food, cases of severe inanition were encountered quite frequently in southern Italy.The obvious dehydration of these emaciated infants on one hand and the poor results obtained with intravenous fluid therapy on the other hand suggested that there existed a severe disturbance of the distribution of body water rather than a simple deficiency in body fluids. Studies under the actual conditions of a war-torn and povertystricken country seemed therefore to be desirable. METHODS AND MATERIAL Clinical materialTwenty-three cases of severe marasmus in infancy and six cases of chronic malnutrition in older children were examined and 55 observations were made. Prior to being admitted to the Annunziata Hospital in Naples these infants had suffered generally from several attacks of gastro-intestinal disturbances, particularly diarrhea and vomiting, which presumably caused their initial loss of 1The present studies are a part of the work of the Italian Medical Nutrition Mission, 1945-46. This Mis-sion was sponsored by the Unitarian Service Committee,

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“…Similar results with the Evans Blue and carbon-monoxide methods have also been obtained in the same normal subjects (25,26).…”

Section: Plasma Proteinssupporting

confidence: 84%

Blood and Extracellular Fluid Studies in Chronic Malnutrition in Infancy 12

Gollan¹

1948

J. Clin. Invest.

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“…of arterial blood were obtained for chemical analysis. An initial plasma volume (PVT,) of 5.5 per cent of body weight was assumed, based on other studies (18). Changes in this volume were calculated from the changes in the hemoglobin concentration and the relative cell volume of anaerobically defibrinated arterial blood.…”

Section: Methodsmentioning

confidence: 99%

Hemodynamic Changes in Salt Depletion and in Dehydration 12

Elkinton¹,

Danowski²,

Winkler³

1946

J. Clin. Invest.

114

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“…Direct evidence lies in the fact that the circulating red cell volume determined by radioactive iron is consistently less than when measured at the same time in the same subject by the dye-plasma-hematocrit method in dogs (2) and in humans (1). Equivocal evidence is the finding of either larger or smaller red cell volume by the carbon monoxide than by the dye technique (3).…”

mentioning

confidence: 98%