Simultaneous determination of four vasoactive phytochemicals in different pharmaceutical preparations by a simple HPLC-DAD method

Abstract

A new, simple isocratic HPLC method was developed and validated for the simultaneous estimation of four vasoactive phytochemicals: ascorbic acid (ASC), rutin (RUT), hesperidin (HSP), and diosmin (DSM) in different pharmaceutical preparations.

Voltammetric Determination of Hesperidin on the Electrode Modified with SnO2 Nanoparticles and Surfactants

“…In this case, chromatography with different types of detectors is the most often applied method for its identification and determination with high selectivity and acceptable sensitivity. High-performance liquid chromatography (HPLC) with UV- [5][6][7][8], diode-array [9,10] and tandem massspectrometric [11][12][13] detection is usually applied for these purposes. Recently, several approaches based on ultra-HPLC with tandem mass-spectrometric detector [14,15] and high-performance thin-layer chromatography with UV- [16] and densitometric [17] detection have been developed.…”

Spider diagram with greenness evaluation metrics for assessing the new synchronous spectrofluorimetric determination of bicalutamide and resveratrol in human plasma

“…Consequently, promising therapeutic prospects for the treatment of PC include phytochemicals, which are naturally occurring alternatives to androgens generated by a wide variety of plants [7, 8]. A phytochemical compound found in grapes, peanuts, and berries called resveratrol (RES) is among the appealing ones.…”

Method Development for the Simultaneous Estimation of Etamsylate and Tranexamic Acid by UPLC/Pda in Bulk and Formulation.

“…[1][2][3] A through literature survey revealed that various analytical and few bioanalytical methods were published to describe the quantification of Ethamsylate and Tranexamic acid in active pharmaceutical ingredient and pharmaceutical dosage forms to study the purity, degradation products by UV-Spectrophotometric method. [5][6][7][8] and RP-HPLC [9][10][11][12][13][14][15] . Our literature survey also revealed that there was no method till date reported using UPLC at nanogram level of lower quantification and identification concentration for these principle components within the short period of time with the good resolution and peak shape.…”