2019
DOI: 10.1364/boe.10.000571
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Simulating orientation and polarization characteristics of dense fibrous tissue by electrostatic spinning of polymeric fibers

Abstract: Phantoms simulating polarization characteristics of soft tissue play an important role in the development, calibration, and validation of diagnostic polarized imaging devices and of therapeutic strategy, in both laboratory and clinical settings. We propose to fabricate optical phantoms that simulate polarization characteristics of dense fibrous tissues by bonding electrospun polylactic acid (PLA) fibers between polydimethylsiloxane (PDMS) substrate with a groove. Increasing the rotational speed of an electrosp… Show more

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Cited by 8 publications
(6 citation statements)
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“…Nowadays, designing and constructing the structures of PLLA materials used for oil–water separation is a widely studied subject. Various methods have been developed to achieve superhydrophobic PLLA materials, such as phase separation, solution-blow spinning, and electrostatic spinning methods. Gu et al fabricated a biodegradable superhydrophobic PLLA nonwoven fabric via a hierarchical micro/nanoparticles assistant method to separate oil and water driven by gravity. Ye et al synthesized a solution-blow spinning strategy to add SiO 2 -modified PLLA nanofiber membranes with excellent oil–water separation performance.…”
Section: Introductionmentioning
confidence: 99%
“…Nowadays, designing and constructing the structures of PLLA materials used for oil–water separation is a widely studied subject. Various methods have been developed to achieve superhydrophobic PLLA materials, such as phase separation, solution-blow spinning, and electrostatic spinning methods. Gu et al fabricated a biodegradable superhydrophobic PLLA nonwoven fabric via a hierarchical micro/nanoparticles assistant method to separate oil and water driven by gravity. Ye et al synthesized a solution-blow spinning strategy to add SiO 2 -modified PLLA nanofiber membranes with excellent oil–water separation performance.…”
Section: Introductionmentioning
confidence: 99%
“… 32 A common material for tissue-mimicking phantoms is polydimethylsiloxane (PDMS) due to its tunability for scattering and absorption. 33 , 34 PDMS is particularly useful for phantoms that mimic highly stretchable organs, such as the bladder. 29 …”
Section: Birefringence In a Tissue-mimicking Materialsmentioning
confidence: 99%
“…32 A common material for tissue-mimicking phantoms is polydimethylsiloxane (PDMS) due to its tunability for scattering and absorption. 33,34 PDMS is particularly useful for phantoms that mimic highly stretchable organs, such as the bladder. 29 Our strategy to introduce birefringence in a tissue-mimicking phantom relies on the photoelastic property of PDMS, which varies as a function of the curing ratio and stretch.…”
Section: Choice Of Materialsmentioning
confidence: 99%
“…(ⅴ) Electrical conductance: scaffolds should allow the engineered constructs to perform the dynamic functions of the heart [25]. (vi) Anisotropy: scaffolds should have an anisotropic microstructure, which has been shown to promote CM alignment and favor cell differentiation and functionality [26][27][28][29][30]. [48].…”
Section: Overview Of Cardiac Tissue Engineering (Cte)mentioning
confidence: 99%