“…3,4,6,7,12 Based on these studies, the grading system most applicable to cytology is the MB nuclear grading system, originally proposed by Fisher et al 9,10 The MB system is based solely on cytologic features-namely, nuclear pleomorphism, delicacy of chromatin strands, presence or absence of nucleoli, and number of mitotic figures. Because of these cytologic criteria, it has been shown that the MB grading system has a very high correlation with histology and is highly reproducible.…”