Silk materials for medical, electronic and optical applications

Fan, Suna; Zhang, Yi; Huang, Xiangyu; Geng, Lihong; Shao, Huili; Hu, Xuechao; Zhang, Yaopeng

doi:10.1007/s11431-018-9403-8

Cited by 53 publications

(29 citation statements)

References 106 publications

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“…Silk's robust safety record in humans and in ongoing clinical trials makes it a highly attractive material for state-of-the-art medical applications [3]. The spun silk fiber can either be used directly or reverse engineered into liquid silk for processing into stimulus-responsive nanomedicines [6], stabilizers for payloads (drugs, proteins and diagnostics) [7], medical sensors [8], hydrogels for tissue engineering [9] and vehicles for drug and cell delivery [6,10,11].…”

Section: Introductionmentioning

confidence: 99%

Emerging Silk Material Trends: Repurposing, Phase Separation and Solution-Based Designs

Seib

2021

Materials

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Silk continues to amaze. This review unravels the most recent progress in silk science, spanning from fundamental insights to medical silks. Key advances in silk flow are examined, with specific reference to the role of metal ions in switching silk from a storage to a spinning state. Orthogonal thermoplastic silk molding is described, as is the transfer of silk flow principles for the triggering of flow-induced crystallization in other non-silk polymers. Other exciting new developments include silk-inspired liquid–liquid phase separation for non-canonical fiber formation and the creation of “silk organelles” in live cells. This review closes by examining the role of silk fabrics in fashioning facemasks in response to the SARS-CoV-2 pandemic.

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Section: Introductionmentioning

confidence: 99%

Emerging Silk Material Trends: Repurposing, Phase Separation and Solution-Based Designs

Seib

2021

Materials

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“…Generally, silk consists of fibrous proteins containing highly repetitive sequences of amino acids: fibroin and sericin. These proteins are arranged into fibers following a highly optimized hierarchical nanostructure, which results in the excellent mechanical properties of silk (strength 610–690 MPa and toughness 70–78 MJm −3 ) [ 38 ]. Silkworm silk is highly biocompatible and easily modifiable, therefore, it finds wide application in diverse areas of medicine, such as tissue engineering, drug delivery, and the development of (bio)sensing devices.…”

Section: Principles Of Mss and Msamentioning

confidence: 99%

“…Silkworm silk is highly biocompatible and easily modifiable, therefore, it finds wide application in diverse areas of medicine, such as tissue engineering, drug delivery, and the development of (bio)sensing devices. Some reviews about the uses of silk- based materials in medicine have been recently published [ 37 , 38 , 39 , 40 , 41 ].…”

Section: Principles Of Mss and Msamentioning

confidence: 99%

Multisensor Systems and Arrays for Medical Applications Employing Naturally-Occurring Compounds and Materials

Pauliukaitė

Voitechovič

2020

Sensors

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The significant improvement of quality of life achieved over the last decades has stimulated the development of new approaches in medicine to take into account the personal needs of each patient. Precision medicine, providing healthcare customization, opens new horizons in the diagnosis, treatment and prevention of numerous diseases. As a consequence, there is a growing demand for novel analytical devices and methods capable of addressing the challenges of precision medicine. For example, various types of sensors or their arrays are highly suitable for simultaneous monitoring of multiple analytes in complex biological media in order to obtain more information about the health status of a patient or to follow the treatment process. Besides, the development of sustainable sensors based on natural chemicals allows reducing their environmental impact. This review is concerned with the application of such analytical platforms in various areas of medicine: analysis of body fluids, wearable sensors, drug manufacturing and screening. The importance and role of naturally-occurring compounds in the development of electrochemical multisensor systems and arrays are discussed.

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Section: Introductionmentioning

confidence: 99%

Fabrication Techniques for Curved Electronics on Arbitrary Surfaces

Tian

Luo

et al. 2020

Adv Materials Technologies

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Curved electronics, which are better coordinated and blended with the natural world due to the characteristics of large contact area, high space adaptability, etc., have been widely used in a quantity of areas ranging from conformal curved antennas and sensors in detection and measurement, to artificial smart skin of aerospace. Recent developments in curved electronics have made an increasing progress to the historic drawbacks of conventional planar electronics, however significant challenges still exist. Here, the main kinds of conformal fabrication technologies, including transfer printing, assembly techniques, curved lithography, conformal inkjet printing, 3D printing, and laser direct writing, are reviewed to realize manufacturing deformable/undeformable electronics on curved or arbitrary surfaces. The processes and features of each technology are comprehensively summarized together with their progress and potential values. Finally, the challenges and opportunities for fabricating conformal electronics on arbitrary surfaces are also discussed.

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Silk materials for medical, electronic and optical applications

Cited by 53 publications

References 106 publications

Emerging Silk Material Trends: Repurposing, Phase Separation and Solution-Based Designs

Emerging Silk Material Trends: Repurposing, Phase Separation and Solution-Based Designs

Multisensor Systems and Arrays for Medical Applications Employing Naturally-Occurring Compounds and Materials

Fabrication Techniques for Curved Electronics on Arbitrary Surfaces

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