Significance of polymethylmethacrylate (PMMA) modification by zinc oxide nanoparticles for fungal biofilm formation

Cierech, Mariusz; Kolenda, Adam; Grudniak, Anna M.; Wojnarowicz, Jacek; Woźniak, Bartosz; Gołaś, Marlena; Swoboda-Kopeć, Ewa; Łojkowski, Witold; Mierzwińska-Nastalska, Elżbieta

doi:10.1016/j.ijpharm.2016.06.052

Cited by 65 publications

(72 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…By combining ZnONPs and acrylic glass, or polymethylmethacrylate (PMMA), the group observed inhibition of fungal biofilm formation that could treat conditions such as denture stomatitis. 138 After several reports of ZnONPs exhibiting selective toxicity toward cancer cells surfaced, Akhtar et al 139 report the selective killing of cancer cells to induce apoptosis after exposure to ZnONPs. The group suggests induced apoptosis of human cancer cells to result from the production of tumor suppressor protein p53.…”

Section: Zinc Nanomaterialsmentioning

confidence: 99%

Antibacterial properties and toxicity from metallic nanomaterials

Vimbela¹,

Ngo²,

Fraze³

et al. 2017

IJN

501

334

View full text Add to dashboard Cite

The era of antibiotic resistance is a cause of increasing concern as bacteria continue to develop adaptive countermeasures against current antibiotics at an alarming rate. In recent years, studies have reported nanoparticles as a promising alternative to antibacterial reagents because of their exhibited antibacterial activity in several biomedical applications, including drug and gene delivery, tissue engineering, and imaging. Moreover, nanomaterial research has led to reports of a possible relationship between the morphological characteristics of a nanomaterial and the magnitude of its delivered toxicity. However, conventional synthesis of nanoparticles requires harsh chemicals and costly energy consumption. Additionally, the exact relationship between toxicity and morphology of nanomaterials has not been well established. Here, we review the recent advancements in synthesis techniques for silver, gold, copper, titanium, zinc oxide, and magnesium oxide nanomaterials and composites, with a focus on the toxicity exhibited by nanomaterials of multidimensions. This article highlights the benefits of selecting each material or metal-based composite for certain applications while also addressing possible setbacks and the toxic effects of the nanomaterials on the environment.

show abstract

Section: Zinc Nanomaterialsmentioning

confidence: 99%

Antibacterial properties and toxicity from metallic nanomaterials

Vimbela¹,

Ngo²,

Fraze³

et al. 2017

IJN

501

334

View full text Add to dashboard Cite

show abstract

“…Several studies suggested methods of disinfection, such as microwave energy, 3 ultrasonic soaking, 4 and incorporation of metal/metal oxide into PMMA. [5][6][7][8][9] Silver nanoparticles (nps) are of interest because of their biocompatibility and antimicrobial effect. 5,9 However, the incorporation of silver nps into PMMA did not improve the mechanical properties and caused discoloration of PMMA.…”

Section: Introductionmentioning

confidence: 99%

“…This metal oxide varies in particle size, with sizes ranging from microns to nanometers. 8,10,11 Many studies demonstrated the effectiveness of these particles on inhibiting the growth of fungi 7,10 and bacteria. [11][12][13][14][15] The inhibition depended on particle size, concentration, and type of microbes.…”

Section: Introductionmentioning

confidence: 99%

Antifungal, optical, and mechanical properties of polymethylmethacrylate material incorporated with silanized zinc oxide nanoparticles

Kamonkhantikul

Arksornnukit

Takahashi

2017

IJN

View full text Add to dashboard Cite

“…46,48,49 In addition, it may have an antifungal effect and may play a preventive role in patients susceptible to fungal infections. 50 On the other hand, one study found an insignificant increase in the hardness of nano-ZrO 2 /PMMA, and its surface roughness was not significantly changed 44 Safi et al, 51 studied the effect of zirconia NP addition on the color properties of PMMA and did not find any noticeable color changes.…”

mentioning

confidence: 99%

PMMA denture base material enhancement: a review of fiber, filler, and nanofiller addition

Gad

Fouda

Al‐Harbi

et al. 2017

IJN

309

319

View full text Add to dashboard Cite

This paper reviews acrylic denture base resin enhancement during the past few decades. Specific attention is given to the effect of fiber, filler, and nanofiller addition on poly(methyl methacrylate) (PMMA) properties. The review is based on scientific reviews, papers, and abstracts, as well as studies concerning the effect of additives, fibers, fillers, and reinforcement materials on PMMA, published between 1974 and 2016. Many studies have reported improvement of PMMA denture base material with the addition of fillers, fibers, nanofiller, and hybrid reinforcement. However, most of the studies were limited to in vitro investigations without bioactivity and clinical implications. Considering the findings of the review, there is no ideal denture base material, but the properties of PMMA could be improved with some modifications, especially with silanized nanoparticle addition and a hybrid reinforcement system.

show abstract

Significance of polymethylmethacrylate (PMMA) modification by zinc oxide nanoparticles for fungal biofilm formation

Cited by 65 publications

References 24 publications

Antibacterial properties and toxicity from metallic nanomaterials

Antibacterial properties and toxicity from metallic nanomaterials

Antifungal, optical, and mechanical properties of polymethylmethacrylate material incorporated with silanized zinc oxide nanoparticles

PMMA denture base material enhancement: a review of fiber, filler, and nanofiller addition

Contact Info

Product

Resources

About