Significance of Gastric Analysis with Particular Reference to the Diagnosis of Zollinger-Ellison Syndrome

Validation of a New Endoscopic Technique to Assess Acid Output in Zollinger–Ellison Syndrome

“…4 Gastric analysis traditionally has been considered the gold standard in the diagnosis of Zollinger-Ellison syndrome (ZES), a less common cause of inappropriate fasting hypergastrinemia. 5,6 To both diagnose and manage the high acid output (AO) state seen in ZES, patients often initially require gastric analysis at 3-month intervals to assess medical therapeutic success. In these patients in particular, it is absolutely critical to develop both a highly accurate and easily used AO assay to follow up disease progression clinically.…”