2016
DOI: 10.1007/s00381-016-3012-7
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Short-term prognostic factors in myelomeningocele patients

Abstract: Extent of the spinal cord defect and the time of surgical correction influenced the short-term outcomes of patients with myelomeningocele. Extensive lesions were associated with higher rates of CNS infections, surgical wound complications, and prolonged hospital stay. Interventions performed within 48 h after birth significantly reduced occurrence of CNS infections. Absence of antenatal hydrocephalus was associated with fewer complications in the first days of life.

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Cited by 22 publications
(15 citation statements)
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“…It was determined that early mortality and morbidity rates decreased in the babies with NTD in the early period. In the literature, 70–91% of newborns diagnosed for meningomyelocele were operated in the first 72 hr (Bülbül et al, ; Rodrigues, Krebs, Matushita, & de Carvalho, ). Bulbul et al found that duration of hospitalization and central nervous system (CNS) infection rate was significantly lower in babies undergone operations due to meningomyelocele in the first 3 days (Bülbül et al, ).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…It was determined that early mortality and morbidity rates decreased in the babies with NTD in the early period. In the literature, 70–91% of newborns diagnosed for meningomyelocele were operated in the first 72 hr (Bülbül et al, ; Rodrigues, Krebs, Matushita, & de Carvalho, ). Bulbul et al found that duration of hospitalization and central nervous system (CNS) infection rate was significantly lower in babies undergone operations due to meningomyelocele in the first 3 days (Bülbül et al, ).…”
Section: Discussionmentioning
confidence: 99%
“…Bulbul et al found that duration of hospitalization and central nervous system (CNS) infection rate was significantly lower in babies undergone operations due to meningomyelocele in the first 3 days (Bülbül et al, ). Rodrigues et al found that the risk of SSS infection was 5.72 times less in babies undergone operations in the first 48 hr (Rodrigues et al, ). Therefore, it is recommended that the operation for the improvement of NTD should be performed within the first 72 hr.…”
Section: Discussionmentioning
confidence: 99%
“…Surgical site infection is a frequent complication in myelomeningocele repair [12]. The prevalence of wound sepsis in this series was 21% which falls within the 12.8-34% reported in the literature [11,12,16,23]. Risk factors for surgical site infection are delayed presentation, size of defect, length of operative procedure and the use of flap reconstruction [11,12].…”
Section: Discussionmentioning
confidence: 71%
“…In the study by Bulbul et al 6 , it was found that the length of hospital stay and the rate of CNS infections were significantly lower in newborns operated on due to myelomeningocele within the first 3 days of life. In the study by Rodrigues et al 32 , the risk of developing CNS infections was found to be 5.72-fold lower in newborns operated on within the first 48 hours. In our study, 62.65% of patients were operated on within the first month of life, and this rate is consistent with that observed in the literature 21,32 .…”
Section: Study Of Hokkaido Did Not Reveal Any Relation Between Serum mentioning
confidence: 89%