Short-term effects of particle size fractions on lung function of late adolescents

Abstract

Although ambient air pollution has been linked to reduced lung function in healthy students, longitudinal studies that compare the response of asthmatic and healthy adolescents are lacking. To evaluate lung function responses to short-term ambient air particulate matter (PM, PM, and PM) levels, we conducted a study on high school students aged 15-18 years. The aim of this study was to assess effects of acute exposure to ambient air particulate matter (PM) on lung function in healthy and asthmatic late adolescents. We examined associations of lung function indices and ambient PM levels in 23 asthmatic and 23 healthy students. Paired-samples T test was used to evaluate the association of exposure to airborne PM concentrations with lung function test results (FVC, FEV, FEV/FVC, and FEF). We observed negative impact of exposure to an increased concentration of ambient air PM, PM, and PM on lung function parameters of asthmatic and healthy late adolescents. These findings are consistent with other similar short-term studies which have confirmed the adverse effect of PM air pollution. These associations were stronger in asthmatic subjects compared with those in healthy ones. There are significant adverse effects of ambient air PM on pulmonary function of adolescents, especially asthmatics.

Chemical composition of PM10 and its effect on in vitro hemolysis of human red blood cells (RBCs): a comparison study during dust storm and inversion

“…S2. Order of ionic components in particles followed NO 3¯> Cl¯> SO 4¯2 > Ca +2 > Na + > K + > Mg +2 > F¯> NH 4 + > NO 2¯d uring dust storm (Fig. S2a) and SO 4¯2 > NO 3¯> NH 4 + > Cl¯> Ca + 2 > Na + > K + > F¯> NO 2¯> Mg +2 during inversion (Fig.…”

“…Ambient air pollution is a global public health concern, especially in the metropolitan areas, that associated with cardiorespiratory diseases, reduced lung function, asthma, chronic bronchitis and increased hospital admissions [1][2][3][4]. Unfortunately, the atmospheric pollution is increasing due to the growth of population, increasing vehicles and urban expansion [5,6].…”

Global Health Impacts of Dust Storms: A Systematic Review

“…Thirty-three articles from almost all regions discussed mortality due to dust storms by means of different health problems, such as increased total non-accidental deaths, 3 , 38 , 39 , 41 , 46 , 53 - 55 , 68 - 82 cardiovascular deaths, 3 , 38 , 39 , 48 , 50 , 53 , 70 , 74 , 77 , 82 - 85 mortality due to acute coronary syndrome ( ACS), 3 , 70 , 81 , 86 and respiratory mortality. 48 , 53 , 55 , 77 , 87 Some studies reported, however, that the number of cases was not increased significantly for all-causes, 43 , 88 respiratory, 38 , 43 cardiovascular, 43 or cerebrovascular mortality.…”

“… 104 Also, some reported no significant association between increased dust particles and angina. 50 Bennett et al 105 reported that the dust storms were not associated with an excess of CVD hospitalizations.…”

“… 46 Chen et al, 47 Kashima et al, 48 and Delangizan 49 also noted that increased PM 10 levels during Asian dust storms increased cardiovascular mortality. Some studies have reported that Middle Eastern dust storms can affect inflammation and coagulation markers in young adults, 28 , 29 have adverse effects on pulmonary function, 50 and increase the number of asthma patients. 51 - 52 Conversely, some studies have either ruled out the possibility of an increase in mortality or hospitalizations of patients due to dust storm exposure or do not consider the increase to be significant.…”