Sexual dysfunction with protease inhibitors

Martínez, Eduardo; Collazos, Julio; Mayo, José; Blanco, Maria-Soledad

doi:10.1016/s0140-6736(99)00593-0

Cited by 46 publications

(27 citation statements)

References 3 publications

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“…Patients lost to follow-up were not reached, which may have lead to a potential overestimation of the correlation between ART and sexual dissatisfaction (as one could hypothesize that people who are lost to follow-up are more likely to feel depressed, since not caring about health is a core symptom of depression). The role of ART in the onset of sexual problems in MLHIV remains unclear, also because of the inconsistency of the results obtained in other studies [6,[15][16][17][18][19][20][21][22]. The lack of a gold standard to define sexual dissatisfaction necessitated defining an arbitrary cutoff point without proven clinical relevance.…”

Section: Discussionmentioning

confidence: 99%

Sexual Satisfaction Among Men Living with HIV in Europe

et al. 2011

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This study determined risk factors for decreased sexual satisfaction among men living with HIV (MLHIV). Self-administered questionnaires were distributed consecutively to all MLHIV attending 17 European HIV treatment centres. The sample included 1,017 MLHIV, among whom 79.2% self-identified as homosexual or bisexual. Sexual satisfaction was measured for five domains of sexual functioning and 33.2% reported low satisfaction in at least one domain. Decreased sexual satisfaction was associated with psychosocial factors, i.e. depression (OR 2.77, P < 0.001), anxiety (OR 1.77, P < 0.001), stress (OR 2.27, P < 0.001) and social factors, such as low partner support (OR 2.28, P < 0.001) and experiences of HIV related discrimination (OR 1.69, P < 0.001). Discussing satisfaction with sexuality should be integrated in regular HIV care, considering patients' personal and relationship-related resources next to medical treatment if indicated.

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Section: Discussionmentioning

confidence: 99%

Sexual Satisfaction Among Men Living with HIV in Europe

et al. 2011

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“…While several studies have demonstrated an association with PIs (1,2,3,5) it is interesting that neither of the two groups that utilised the IIEF found a link with a particular class of medications (4,6).…”

Section: Erectile Dysfunctionmentioning

confidence: 99%

“…Deleted: There have been numerous reports of sexual dysfunction in HIV positive men with prevalence rates of up to 70% being described (1)(2)(3)(4)(5)(6) The primary objectives of this study therefore are to establish the prevalence of erectile dysfunction (EDF) and low sexual desire (LSD) in both ARV naïve and experienced HIV positive men attending HIV outpatient centres across Europe and to define the variables associated with sexual dysfunction. Due to the large number of variables that are potentially contributors to dysfunction a large amount of data relating to these variables was collected.…”

Section: Deleted: Sep_06mentioning

confidence: 99%

Sexual dysfunction in HIV-positive men is multi-factorial: A study of prevalence and associated factors

Catalán²,

et al. 2007

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“…Although HAART can bring back good physical shape, it has been speculated that antiretroviral therapy could be associated with sexual dysfunction. Several studies have described sexual dysfunction in men receiving HAART and argue about whether or not treatments containing protease inhibitors increase sexual dysfunction (Catalan and Meadows 2000;Collazos et al 2002;Colson and Sax 2000;Lallemand et al 2002;Martinez et al 1999;Schrooten et al 2001). These studies mainly focused on men and analysed sexual dysfunction from a clinical point of view, focusing on the type of HAART regimen prescribed.…”

Section: Introductionmentioning

confidence: 99%

Sexual Difficulties in People Living with HIV in France—Results from a Large Representative Sample of Outpatients Attending French Hospitals (ANRS-EN12-VESPA)

et al. 2008

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We analysed sexual difficulties in a nationally representative sample of HIV-infected outpatients in France. Analyses were restricted to the 1,812 HIV-treated participants who reported at least one sexual partner during the 12 months prior to the study. The sample included 40.6% homosexual men and 24.4% women; 68.1% had a steady partner and 48.2% reported casual partners. Sexual difficulties were reported by 33.3% of the selected individuals and were more frequent in those with low sexual activity. Immuno-virological outcomes were not associated with sexual difficulties. After multiple adjustment for sexual frequency and antidepressant consumption, it was found that a larger HIV-network, reporting HIV-discrimination from friends and/or sexual partners, suffering from lipodystrophy and reporting very disturbing HIV-related symptoms were all significantly associated with sexual difficulties. HIV and HIV-treatment experience are associated with sexual difficulties. Psychological support focused on HIV-experience should be tested as a possible tool for improving sexual quality of life.

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Sexual dysfunction with protease inhibitors

Cited by 46 publications

References 3 publications

Sexual Satisfaction Among Men Living with HIV in Europe

Sexual Satisfaction Among Men Living with HIV in Europe

Sexual dysfunction in HIV-positive men is multi-factorial: A study of prevalence and associated factors

Sexual Difficulties in People Living with HIV in France—Results from a Large Representative Sample of Outpatients Attending French Hospitals (ANRS-EN12-VESPA)

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