Sexual dysfunction in HIV-positive men is multi-factorial: A study of prevalence and associated factors

Asboe, David; Catalán, José; Mandalia, Sundhiya; Dedes, Nikos; Florence, Éric; Schrooten, Ward; Noëstlinger, Christiana; Colebunders, Robert

doi:10.1080/09540120701209847

Cited by 93 publications

(129 citation statements)

References 17 publications

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“…This has been related to psychological factors (432) and to duration of antiretroviral therapy, but no association has been found with any specific class of antiretrovirals (439). Sexual problems such as erectile dysfunction have also been associated with using sex as an avoidant strategy to cope with daily life stress and sexual risk taking in casual encounters (430).…”

Section: Clinical Features and Aetiologymentioning

confidence: 99%

2016 United Kingdom national guideline on the sexual health care of men who have sex with men

et al. 2018

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Section: Clinical Features and Aetiologymentioning

confidence: 99%

2016 United Kingdom national guideline on the sexual health care of men who have sex with men

et al. 2018

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“…8,9 Premature ejaculation, erectile dysfunction, and hypogonadism have been identified most often in relation to sexual dysfunction in comparison to uninfected populations. 10,11 Sexual dysfunction among men who have sex with men with HIV has ranged from 10% to 30% of clinic populations. 11 Specifically, studies of women with HIV have been documented, with 30% to 41% of hypoactive sexual function, such as less sexual interest and reduced satisfaction when compared to uninfected women.…”

Section: Introductionmentioning

confidence: 99%

Examining Sexual Function Among Individuals With HIV in a Midwestern US Urban Outpatient Clinic Setting

Shacham

López

Souza

et al. 2017

J Int Assoc Provid AIDS Care

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The role of sexual function and its impact on HIV management have been inadequately evaluated. A cross-sectional study in 2009 of 202 patients with HIV were recruited to examine sexual function and psychosocial/HIV management factors. Analyses assessed the relationship between sexual function, sociodemographic factors, biomedical markers, and depressive symptomology. The M-Estimator compared differences in the means of the HIV, cancer survivors, and the normative cohorts. More than 75% were on combination antiretroviral therapy, of which 70% had suppressed HIV viral loads. Patients with unsuppressed HIV viral loads reported lower rates of arousal. Better overall health was associated with higher rates of overall sexual function, arousal, and interest. Compared to the normative and cancer survivor cohorts, mean sexual function was significantly lower in the HIVinfected cohort in all subscales, except for masturbation. These findings suggest lower sexual function impacts individuals with HIV in ways related to negative biomedical and psychosocial factors.

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“…It is now well established that dysfunction in the endocrine system, as a result of HIV infection, impacts adrenal, [82][83][84][85][86] thyroid, 85,87,88 pituitary, [89][90][91][92][93][94][95] and gonadal function (Table 1), 85,91,96,97 and endocrinopathies in HIV-positive patients have been the subject of a number of excellent review articles. 86,88,[93][94][95][96][97][98][99] Many aspects of the endocrine dysfunction can be attributed to opportunistic infections as well as to HIV infection.…”

Section: Lipid and Bone Metabolism In Hiv/haartmentioning

confidence: 99%

Human Immunodeficiency Virus and Highly Active Antiretroviral Therapy–Associated Metabolic Disorders and Risk Factors for Cardiovascular Disease

Anuurad

Semrad

Berglund

2009

Metabolic Syndrome and Related Disorders

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The successful introduction of highly active antiretroviral therapy (HAART), a combination of potent antiretroviral agents, including protease inhibitors, nucleoside reverse transcriptase inhibitors, and nonnucleoside reverse transcriptase inhibitors, has impacted positively on morbidity and mortality among human immunodefi ciency virus (HIV)-positive patients. Over time, HAART has been associated with a number of metabolic and anthropometric abnormalities, including dyslipidemia and insulin resistance as well as subcutaneous fat loss and abdominal obesity, potentially contributing to cardiovascular risk. Recent studies have more fi rmly established that both HIV infection and HAART might increase the risk of clinical cardiovascular events. Furthermore, whereas HIV/HAART is associated with multiple aspects of endocrine dysfunction, there has been less focus on bone disease, although some studies indicate a higher prevalence of osteoporosis among HIV-positive subjects compared to HIV-negative controls. The relationship between bone and fat metabolism under HIV-positive conditions deserves further attention, and available data suggest the possibility of an intriguing connection. In the future, an increasing population of aging HIV-positive patients with a spectrum of antiretroviral therapies and accumulation of endocrine abnormalities and conventional cardiovascular risk factors will present preventive and therapeutic challenges to our health-care system.

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Sexual dysfunction in HIV-positive men is multi-factorial: A study of prevalence and associated factors

Cited by 93 publications

References 17 publications

2016 United Kingdom national guideline on the sexual health care of men who have sex with men

2016 United Kingdom national guideline on the sexual health care of men who have sex with men

Examining Sexual Function Among Individuals With HIV in a Midwestern US Urban Outpatient Clinic Setting

Human Immunodeficiency Virus and Highly Active Antiretroviral Therapy–Associated Metabolic Disorders and Risk Factors for Cardiovascular Disease

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