Severe Erythema Multiforme With Intestinal Involvement

Crawford, G. Marshall; Luikart, Ralph

doi:10.1001/jama.1949.82900440003006a

Cited by 13 publications

(2 citation statements)

References 7 publications

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“…OTHER LESIONS Cameron et al (1966) reported four cases of erythema multiforme in association with ulcerative colitis, including case 17 of our series, and, after reviewing the literature, concluded that in all cases except one (Crawford and Luikart, 1949) the skin condition could have been due to a drug. In our case 13 the erythema multiforme occurred during toxaemia of pregnancy, an association which is well known.…”

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confidence: 62%

Skin lesions in ulcerative colitis.

Johnson¹,

Wilson²

1969

Gut

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This paper is a study of the skin complications of ulcerative colitis. Between theyearsl949and 1965,415 patients, 230 women and 185 men, were admitted to the Central Middlesex Hospital suffering from this disease. Our object has been to determine the incidence and pattern of the skin disorders in this group and to try to discover if there is any relationship between the skin disease and the severity and extent of the colitis. Twenty patients had dermatoses associated with the bowel disorder and 12 were examined by one of us (H.T.H.W.). The morphological classification is based on these personally observed cases. The sex incidence showed that whereas 55 % of the whole series of colitics were women, 14 (70%) of those who had skin complications were women. Seven developed different types of lesion at different stages of the disease. The main conditions found were erythema nodosum (eight cases), pyoderma gangrenosum (seven cases), papulo-necrotic lesions (five cases), and ulcerating erythematous plaques on the shins (three cases). ERYTHEMA NODOSUMTender red nodes, generally appearing on the shins and associated with exacerbations of the colitis, occurred in eight patients, all women.The age of onset of erythema nodosum varied from 21 to 52 years (mean 29 years) and the skin lesions developed at any time from the onset of the first attack of colitis to 16 years later (mean 5*5 years). Although the attacks of erythema nodosum coincided with exacerbations of the colitis there was no correlation with the extent of the disease.

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confidence: 62%

Skin lesions in ulcerative colitis.

Johnson¹,

Wilson²

1969

Gut

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“…EM has been often reported in patients with UC and in most cases it was related to administered drugs (mainly sulfonamides) for its treatment. However, sporadic cases of untreated UC associated with EM have also been described and UC is regarded as an independent triggering factor of EM [8,9]. The possibility that UC could be the causative factor of EM in our patient cannot be definitely ruled-out but it is very unlikely since she was suffering from recalcitrant inflammatory bowel disease for many years without revealing any signs of skin disease.…”

Section: Case Discussionmentioning

confidence: 77%