Golimumab-associated persistent erythema multiforme in a patient with ulcerative colitis in full remission

Successful management of tumor necrosis factor‐α inhibitor‐induced erythema multiforme by switching to a Janus kinase inhibitor in a patient with rheumatoid arthritis and ulcerative colitis

“…Dear Editor, Tumor necrosis factorα (TNFα) inhibitors are potent treatments for autoimmune diseases, such as rheumatoid arthritis (RA) and ulcerative colitis (UC). However, TNFα inhibitors may paradoxically induce erythema multiforme (EM), [1][2][3] an immune-mediated disorder associated with hypersensitivity reactions to drugs and viral or bacterial infections. 4 Here, we report a case of EM induced by TNFα inhibitors successfully treated by switching to a Janus kinase (JAK) inhibitor.…”