Severe abdominal complications after transvaginal ultrasonographically guided retrieval of oocytes for in vitro fertilization and embryo transfer

Dicker, Dov; Ashkenazi, Jacob; Feldberg, Dov; Levy, Tally; Dekel, Arie; Ben‐Rafael, Zion

doi:10.1016/s0015-0282(16)55997-4

Cited by 151 publications

(65 citation statements)

References 5 publications

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“…124 Although patient-important vaginal bleeding appears to occur in up to 2% to 3% of patients, signifi cant intraabdominal bleeding is much less common ( Յ 0.5% procedures) (Table S7). 120,[125][126][127][128][129][130][131][132] Whether these risks are increased with antithrombotic prophylaxis is uncertain.…”

Section: Prevention Of Vte In Patients Undergoing Assisted Reproductimentioning

confidence: 99%

VTE, Thrombophilia, Antithrombotic Therapy, and Pregnancy

Bates

Greer

Middeldorp

et al. 2012

Chest

1,287

591

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Summary of RecommendationsNote on Shaded Text: Throughout this guideline, shading is used within the summary of recommendations sections to indicate recommendations that are newly added or have been changed since the publication of Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Recommendations that remain unchanged are not shaded. Abbreviations: APLA 5 antiphospholipid antibody; aPPT 5 activated partial thromboplastin time; HIT 5 heparin-induced thrombocytopenia; INR 5 international normalized ratio; LMWH 5 low-molecular-weight heparin; NNT 5 number needed to treat; PE 5 pulmonary embolism; RR 5 risk ratio; UFH 5 unfractionated heparin

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Section: Prevention Of Vte In Patients Undergoing Assisted Reproductimentioning

confidence: 99%

VTE, Thrombophilia, Antithrombotic Therapy, and Pregnancy

Bates

Greer

Middeldorp

et al. 2012

Chest

1,287

591

View full text Add to dashboard Cite

show abstract

“…Pelvic infection was controlled through oophorectomy with laparotomy in three, and colpotomy in six, of these patients [18]. In their series of 2.495 patients, Roest et al detected pelvic infection in six (0.24%) patients.…”

Section: Discussionmentioning

confidence: 95%

“…[16,17]. Acute haemorrhage from the ovary, and bleeding or hematomas due to vascular damage in the uterus, ovary, and iliac vein are very rare (0.04-0.07%), but may require surgical intervention when they do occur [16,18]. Dessole et al reported mean blood loss after a routine OPU of 230 mL [19].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of complications developing during and after transvaginal ultrasound — guided oocyte retrieval

2018

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Objectives: To investigate the complications of the oocyte retrieval procedure currently used in in vitro fertilisation. Material and methods:We examined 1.031 patients who underwent oocyte retrieval in the IVF unit of our hospital for complications developed during and after the procedure. Results:No complications developed related to sedation or general anaesthesia. Vaginal bleeding was observed in 3.1% of the patients. There was no intra-abdominal bleeding or pelvic organ injuries requiring surgery. Two patients developed pelvic abscesses. Ovarian hyperstimulation syndrome (OHSS) occurred in 1.45% of the patients. Almost all of the patients tolerated the oocyte retrieval process well. After the procedure, only 2% of the patients described their pain as severe, and 0.4% as the worst pain they had ever experienced. Conclusions:The most common complication during oocyte retrieval is vaginal bleeding, which is largely controlled by buffer application. In conclusion, the oocyte retrieval process can be considered a safe procedure.

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“…Other complications: Other complications of unoperated endometriomas include risk of causing the rupture of the endometrioma, 20 possible follicular fluid contamination with endometrioma content, difficulties during oocyte retrieval 21 and increased obstetric complications, such as preterm birth or intrauterine growth restriction. 22 Data regarding the first risk is anecdotal, whereas the effects of endometriotic fluid on the oocyte quality are still debated.…”

Section: Progression Of Endometriosismentioning

confidence: 99%

Endometrioma and ART: Does the Needle Work?

Hagargi¹,

Patil²

2011

International Journal of Infertility &Amp; Fetal Medicine

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Aim and Objectives:The aim of this study was to see if the fertility outcome improved when IVF/ICSI was done after administration of GnRH analogs and cyst aspiration in comparison with patients in whom either only cyst aspiration or only GnRh analogs were administered. Materials and methods:This was a prospective study done in a tertiary level ART center which included 30 patients over a span of 5 years from 2004 to 2009. All of them had endometriomas and underwent assisted reproductive techniques (ART) either after cyst aspiration with or without GnRH analog pretreatment or only GnRH analog pretreatment. Depending on the pretreatment received, they were classified into three groups: • Group B: Both GnRH analog and cyst aspiration • Group C: Only cyst aspiration • Group G: Only GnRH analog. The patients were not randomized.The number of days required for stimulation, total dose of stimulation required, number of oocytes obtained, quality of embryos, and the pregnancy rates for each group were tabulated for comparison. Statistical analysis:The significance of the difference in ART outcome after the different modalities of pretreatment, which was estimated in terms of pregnancy rates was evaluated by calculating the p-value.Observations and results: Significant difference was observed between the pregnancy rates in the three groups, with the maximum pregnancy rate in group B, followed by the group G and then the group C. The p-value showed a trend, though not statistically significant, indicating the need for larger prospective studies with greater number of subjects. Conclusion:Pretreating endometriomas by aspirating the cysts and administering three doses of GnRH analog depot preparation prior to IVF/ICSI seems to be better than administering GnRH analog depot preparation alone or aspirating the cysts alone in terms of the number of days required for stimulation, the number of oocytes obtained, and the clinical pregnancy rates.

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Severe abdominal complications after transvaginal ultrasonographically guided retrieval of oocytes for in vitro fertilization and embryo transfer

Cited by 151 publications

References 5 publications

VTE, Thrombophilia, Antithrombotic Therapy, and Pregnancy

VTE, Thrombophilia, Antithrombotic Therapy, and Pregnancy

Evaluation of complications developing during and after transvaginal ultrasound — guided oocyte retrieval

Endometrioma and ART: Does the Needle Work?

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