Sesquiterpenes from the roots of<i>Illicium oligandrum</i>

Lü, Hai-Ning; Ma, Shuang‐Gang; Liu, Yun‐Bao; Qu, Jing; Li, Yong; Xu, Song; Zhu, Hongxiang; Yu, Shi‐Shan

doi:10.1080/10286020.2015.1039524

Cited by 14 publications

(4 citation statements)

References 14 publications

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“…And among the two, the spirooliganone B was highly effective against the coxsackie virus B3 and influenza virus A (H3N2) with IC 50 values of 3.70-5.05 μM than the spirooliganone A compound by a biosynthetic pathway which includes a hetero-Diels-Alder reaction process of the epimers (Ma et al, 2013). Similarly Lü et al (2015) has also isolated the oligandrin and oligandric acid from the roots of…”

Section: Antiviral Effects Of Active Constituents From Samentioning

confidence: 99%

Star anise (Illicium verum): Chemical compounds, antiviral properties, and clinical relevance

Patra

Das

Bose³

et al. 2020

Phytotherapy Research

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Medicinal herbs are one of the imperative sources of drugs all over the world. Star anise (Illicium verum), an evergreen, medium-sized tree with star-shaped fruit, is an important herb with wide distribution throughout southwestern parts of the Asian continent. Besides its use as spice in culinary, star anise is one of the vital ingredients of the Chinese medicinal herbs and is widely known for its antiviral effects. It is also the source of the precursor molecule, shikimic acid, which is used in the manufacture of oseltamivir (Tamiflu ® ), an antiviral medication for influenza A and influenza B. Besides, several other molecules with numerous biological benefits including the antiviral effects have been reported from the same plant. Except the antiviral potential, star anise possesses a number of other potentials such as antioxidant, antimicrobial, antifungal, anthelmintic, insecticidal, secretolytic, antinociceptive, antiinflammatory, gastroprotective, sedative properties, expectorant and spasmolytic, and estrogenic effects. This review aimed to integrate the information on the customary attributes of the plant star anise with a specific prominence on its antiviral properties and the phytochemical constituents along with its clinical aptness. K E Y W O R D S antiviral, Illicium verum, oseltamivir, shikimic acid, star anise, Tamiflu

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Section: Antiviral Effects Of Active Constituents From Samentioning

confidence: 99%

Star anise (Illicium verum): Chemical compounds, antiviral properties, and clinical relevance

Patra

Das

Bose³

et al. 2020

Phytotherapy Research

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“…Illicium oligandrum ( I. oligandrum ) belongs to the family of Magnoliaceae , being a rich source of seco-prezizaane type sesquiterpenes [ 203 ]. It is known to have antiviral activity against herpes simplex virus type 2, coxsackie virus and influenza virus [ 204 , 206 ].…”

Section: Other Medicinal Plants In Use Against Various Viral Infecmentioning

confidence: 99%

Plants-Derived Biomolecules as Potent Antiviral Phytomedicines: New Insights on Ethnobotanical Evidences against Coronaviruses

Siddiqui

Danciu

Ashraf

et al. 2020

Plants

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SARS-CoV-2 infection (COVID-19) is in focus over all known human diseases, because it is destroying the world economy and social life, with increased mortality rate each day. To date, there is no specific medicine or vaccine available against this pandemic disease. However, the presence of medicinal plants and their bioactive molecules with antiviral properties might also be a successful strategy in order to develop therapeutic agents against SARS-CoV-2 infection. Thus, this review will summarize the available literature and other information/data sources related to antiviral medicinal plants, with possible ethnobotanical evidence in correlation with coronaviruses. The identification of novel antiviral compounds is of critical significance, and medicinal plant based natural compounds are a good source for such discoveries. In depth search and analysis revealed several medicinal plants with excellent efficacy against SARS-CoV-1 and MERS-CoV, which are well-known to act on ACE-2 receptor, 3CLpro and other viral protein targets. In this review, we have consolidated the data of several medicinal plants and their natural bioactive metabolites, which have promising antiviral activities against coronaviruses with detailed modes of action/mechanism. It is concluded that this review will be useful for researchers worldwide and highly recommended for the development of naturally safe and effective therapeutic drugs/agents against SARS-CoV-2 infection, which might be used in therapeutic protocols alone or in combination with chemically synthetized drugs.

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“…After 2 h of viral adsorption (37 °C), the monolayers were washed by PBS and incubated with or without test compounds in the maintenance medium (37 °C). Cytopathogenic effect (CPE) caused by viral invasion was evaluated when the viral control group reached a level of 4 and the antiviral activity of test compounds was determined according to the Reed and Muench method192021.…”

Section: Methodsmentioning

confidence: 99%

Rhodomollins A and B, two Diterpenoids with an Unprecedented Backbone from the Fruits of Rhododendron molle

Liu

Yan

et al. 2016

Sci Rep

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Two new grayanoids, rhodomollin A (1) and rhodomollin B (2), possessing an unprecedented D-homo grayanane carbon skeleton, were isolated from the fruits of Rhododendron molle. The structures of 1 and 2 were fully characterized using a combination of spectroscopic analyses and X-ray crystallography. Rhodomollin B (2) exhibited modest activity against influenza virus A/95-359, with an IC50 value of 19.24 μM.

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Sesquiterpenes from the roots ofIllicium oligandrum

Cited by 14 publications

References 14 publications

Star anise (Illicium verum): Chemical compounds, antiviral properties, and clinical relevance

Star anise (Illicium verum): Chemical compounds, antiviral properties, and clinical relevance

Plants-Derived Biomolecules as Potent Antiviral Phytomedicines: New Insights on Ethnobotanical Evidences against Coronaviruses

Rhodomollins A and B, two Diterpenoids with an Unprecedented Backbone from the Fruits of Rhododendron molle

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