Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes

Iranshahi, Mehrdad; Arfa, Peyman; Ramezani, Mohammad; Jaafari, Mahmoud Reza; Sadeghian, Hamid; Bassarello, Carla; Piacente, Sonia; Pìzza, Cosimo

doi:10.1016/j.phytochem.2006.11.002

Cited by 159 publications

(110 citation statements)

References 35 publications

(31 reference statements)

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“…Based on the findings, Ferula spp. have been turned out to be a source of bioactive phytochemicals such as sesquiterpene/ sesquiterpene coumarin derivatives (Iranshahi et al 2004(Iranshahi et al , 2007(Iranshahi et al , 2008d, and sulphur-containing compounds (Iranshahi et al 2003(Iranshahi et al , 2006(Iranshahi et al , 2008bIranshahi 2012). …”

Section: Introductionmentioning

confidence: 99%

Sulphur-containing compounds in the essential oil ofFerula alliacearoots and their mass spectral fragmentation patterns

Kasaian

Asili

Iranshahi

2016

Pharmaceutical Biology

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Section: Introductionmentioning

confidence: 99%

Sulphur-containing compounds in the essential oil ofFerula alliacearoots and their mass spectral fragmentation patterns

Kasaian

Asili

Iranshahi

2016

Pharmaceutical Biology

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“…Galbanic acid was extracted from galbanium resin available in domestic market according to the procedure described by Iranshahi and colleagues [15]. All other chemicals used in this study including anhydrous ferric chloride , a 5% (v/v) solution of bromine in ethyl alcohol, and all solvents were purchased from Merk KGaA.…”

Section: Methodsmentioning

confidence: 99%

Comparative study on the effects of galbanic acid, galbanic ferric salt and tetrabromo galbanic acid on photo-oxidative degradation of linear low density (LLDPE) films

Shahmir¹,

Asempour

2012

E-Polymers

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Galbanic acid (GA) is known as an effective photo-sensitizing agent in polyethylene. This paper reports the comparative studies on photo-oxidative degradation of LLDPE films in the presence of varying amounts of galbanic ferric salt (Fe-GA), tetrabromo galbanic acid (Br-GA), GA at the optimum concentration of 0.2% (w/w) and the pure polymer film, exposed to Ultra-Vitalux sun lamp. The degradation rate was monitored through the changes in mechanical properties (retained elongation at break and retained tensile strength) and also carbonyl index. The results obtained revealed that Fe-GA efficiency in enhancing oxidation rate of polymer upon UV exposure is remarkably much more than of GA. In contrast, Br-GA is responsible for initiating photo-oxidation of the polymer and has negligible effects on the rate of degradation. Based on the results obtained, it was proposed that the photo-activity of GA in the polymer arises from the C=C bond present in the side group attached to aromatic lacton rings of additive molecule, probably through its reaction with singlet oxygen and subsequent generation of hydroperoxide. This mechanism in combination with catalytic effect of iron (III) accounted for the higher effect of Fe-GA in accelerating photo-oxidation rate of the polymer.

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“…The most of the sesquiterpene coumarins were stored in the root part [35] which may be deliberated as potential biological compounds for the treatment of malignancies. [36] F. asafoetida has been reported to possess ferulic acid and farnesiferols which can prevent angiogenesis, vascular endothelial growth factor accelerated processes and the development of mouse Lewis lung cancer in mice. [33] In this study, the methanol extract is more cytotoxic compared to the ethanol extract.…”

Section: Antidiabetic Activitymentioning

confidence: 99%

Untitled

Upadhyay

2017

IJGP

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Ferula asafoetida Linn. is a chief source of Asafoetida, a sturdy, obstinate and sulfurous odor, and oleo-gumresin of medicinal and nutritional significance. Asafoetida is used in food as a flavoring agent and also has been used as traditional medicine for many diseases in the world. Recent studies have shown numerous promising activities mostly muscle relaxant, memory enhancing, digestive enzyme, antioxidant, antispasmodic, hypotensive, hepatoprotective, antiviral, antifungal, anticancer, anxiolytics, and anthelmintic activities. It is used in the prevention and treatment of several problems such as unwanted abortion, unusual pain, sterility, and mainly ailment for women such as difficult and excessive menstruation and leukorrhea. Moreover, it is used for stomach pressure, flatulence, low acid levels in the stomach, and loose stools. This review deals with study of various phytoconstituents, pharmacological, and therapeutic effects of Asafoetida.

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Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes

Cited by 159 publications

References 35 publications

Sulphur-containing compounds in the essential oil ofFerula alliacearoots and their mass spectral fragmentation patterns

Sulphur-containing compounds in the essential oil ofFerula alliacearoots and their mass spectral fragmentation patterns

Comparative study on the effects of galbanic acid, galbanic ferric salt and tetrabromo galbanic acid on photo-oxidative degradation of linear low density (LLDPE) films

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