2010
DOI: 10.1016/j.diabres.2009.10.010
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Serum N-terminal-pro-brain natriuretic peptide (NT-pro-BNP) and homocysteine levels in type 2 diabetic patients with asymptomatic left ventricular diastolic dysfunction

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Cited by 21 publications
(13 citation statements)
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“…Monitoring non-conventional risk biomarkers for PAD in T2DM may be particularly important for the prevention and treatment of PAD. BNP levels are known to be elevated in T2DM patients with asymptomatic diastolic dysfunction [23]. It has been acknowledged that subjects with higher BNP levels are more likely to have conventional cardiovascular risk factors (e.g., hypertension [24], ischemic stroke [25,26], and chronic kidney disease [27]).…”
Section: Discussionmentioning
confidence: 99%
“…Monitoring non-conventional risk biomarkers for PAD in T2DM may be particularly important for the prevention and treatment of PAD. BNP levels are known to be elevated in T2DM patients with asymptomatic diastolic dysfunction [23]. It has been acknowledged that subjects with higher BNP levels are more likely to have conventional cardiovascular risk factors (e.g., hypertension [24], ischemic stroke [25,26], and chronic kidney disease [27]).…”
Section: Discussionmentioning
confidence: 99%
“…Abnormalities in diastolic function are often misdiagnosed as this condition does not always produce signs and symptoms of HF, which leaves patients predisposed to symptomatic HF and cardiac necrosis due to the delay in treatment (31). The early diagnosis of LV diastolic dysfunction during its initial phase facilitates the initiation of effective treatment with the purpose of halting the progress of the disease and delaying the development of symptomatic HF (32). Echocardiography, using both Doppler measurements of transmitral and pulmonary vein blood flow velocities and tissue Doppler imaging, is a widely accepted method for the clinical analysis of diastole (33).…”
Section: Endpoint Events ----------------------------------------------mentioning
confidence: 99%
“…Early diagnosis of LV diastolic dysfunction in an initial phase enables the start of effective treatment, which functions by stopping the progress of the disease and delaying the development of symptomatic HF (33). Analysis of the diastole by means of echocardiography, using Doppler measurements of transmitral and pulmonary vein blood flow velocities and tissue Doppler imaging, is widely accepted for clinical purposes (34). However, this type of assessment is expensive as it requires complex equipment, time-consuming as it involves the analysis of numerous variables and difficult as it must be performed by a skilled and trained operator (35).…”
Section: Discussionmentioning
confidence: 99%