Serum isoamylases and liver diseases.

Tsianos, E.V.; Jalali, Mohammad Taha; Gowenlock, A. H.; Braganza, JM

doi:10.1136/jcp.39.4.464-c

Cited by 4 publications

(2 citation statements)

References 9 publications

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“…Increases in serum amylase while drinking are frequently observed in cases of hepatic cirrhosis, but the amylase involved originates from the salivary glands (Hatta et al, 1987;Tsianos et al, 1986). In another report, acute and chronic alcohol intoxication also caused high levels of serum salivary isoamylase (Bloch et al, 1984).…”

Section: Discussionmentioning

confidence: 99%

Low Serum Amylase Levels in Drinking Alcoholics

Maruyama

Takahashi

Okuyama

et al. 2003

Alcoholism Clin & Exp Res

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In cases of heavy alcohol consumption, a decrease in the production or secretion of pancreatic isoamylase and salivary isoamylase while drinking could happen. It was thus suggested that the increase in serum amylase might be due to the fact that this situation is improved by abstinence, plus the fact that excretion of amylase in urine increases during alcohol consumption, and abstinence brings about a decline in such excretion. Measurement of total serum amylase is not appropriate for diagnosing pancreatitis in alcoholic patients or those who consume large quantities of alcohol.

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Section: Discussionmentioning

confidence: 99%

Low Serum Amylase Levels in Drinking Alcoholics

Maruyama

Takahashi

Okuyama

et al. 2003

Alcoholism Clin & Exp Res

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“…Elevation of serum pancreatic enzymes has been noted in adult patients with liver diseases but no clinical symptoms or signs of pancreatic diseases were described [22,23] . A decreased hepatic metabolism of these enzymes was speculated as evidenced by high prevalence of hyperamylasemia (35%) and hyperlipasemia (21%) without associated pancreatic abnormalities on ultrasonography in patients with chronic viral liver diseases, especially cirrhosis [24] .…”

Section: Discussionmentioning

confidence: 99%