Serum biomarkers for nutritional status as predictors in COVID-19 patients before and after vaccination

Vaz-Rodrigues, Rita; Mazuecos, Lorena; Villar, Margarita; Urra, José Miguel; Gortázar, Christian; Fuente, José de la

doi:10.1016/j.jff.2023.105412

Cited by 12 publications

(5 citation statements)

References 73 publications

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“…In accordance, some studies have already evaluated the nutritional status of patients with COVID-19, based on serum markers, such as Retinol Binding Protein (RBP) in the period before and after vaccination. These studies saw that individuals after vaccination maintained RBP at higher levels, re ecting that vaccination would be able to reduce comorbidities and protein-muscle impairment [31].…”

Section: Discussionmentioning

confidence: 99%

Relationship between sarcopenia and cachexia with prognostic markers of middle-aged and older inpatients with COVID-19: a case-control study

Júnior

Pereira

Benjamim

et al. 2023

Preprint

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Purpose:SARS-CoV-2 infection can lead to various manifestations beyond an inflammatory response, such as anorexia, hyposmia, and other symptoms that may increase the risk of nutritional disorders. Sarcopenia and cachexia (nutritional disorders) are conditions that appear to influence COVID-19 evolution. Thus, this study aimed to evaluate sarcopenia and cachexia in hospitalized patients with COVID-19, verifying their clinical impacts and relationship with prognostic markers. Methods: This is a case-control study involving inpatients with and without a COVID-19 diagnosis. The occurrence of sarcopenia was evaluated according to European Working Group on Sarcopenia 2 criteria, and cachexia was also evaluated. Inflammatory markers and the 4C Mortality Score were evaluated. Results: The groups were similar regarding age (p = 0.656), sex (p = 0.777), presence of comorbidities (type 2 diabetes p = 0.659; systemic arterial hypertension p = 0.427), and Body Mass Index (p = 0.657). The frequency of sarcopenia and cachexia in patients with COVID-19 was 21.9% and 28.1%, respectively. Sarcopenic patients with COVID-19 had a higher risk of death (4C Mortality Score) (p = 0.038). The occurrence of sarcopenia or cachexia within the COVID-19 group was not associated with inflammatory biomarkers or a higher number of COVID-19 symptoms (p > 0.05). Conclusion: The presence of sarcopenia among COVID-19 patients increased the risk of mortality.

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Section: Discussionmentioning

confidence: 99%

Relationship between sarcopenia and cachexia with prognostic markers of middle-aged and older inpatients with COVID-19: a case-control study

Júnior

Pereira

Benjamim

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…In accordance, some studies have already evaluated the nutritional status of patients with COVID-19, based on serum markers, such as Retinol Binding Protein (RBP) in the period before and after vaccination. These studies saw that individuals after vaccination maintained RBP at higher levels, reflecting that vaccination would be able to reduce comorbidities and protein-muscle impairment [ 31 ].…”

Section: Discussionmentioning

confidence: 99%

Relationship between sarcopenia and cachexia with prognostic markers of middle-aged and older inpatients with COVID-19: a case–control study

et al. 2023

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Key summary points Aim To identify the influence of sarcopenia and cachexia in prognostic markers in COVID-19 inpatients. Findings Sarcopenia is presented as a risk factor for mortality in COVID-19 inpatients. Message The accurate evaluation of nutritional abnormalities in hospitalized patients diagnosed with COVID-19 may help to reduce the risk for adverse outcomes.

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“…Diet and nutritional status of individuals have been reported to affect COVID-19 prevalence and disease course [30], particularly in populations with limited access to medical resources [31]. The relatively low incidence of COVID-19 in our municipality when compared to rural areas in developing countries may be influenced by a better nutritional status in these individuals [32].…”

Section: Discussionmentioning

confidence: 99%

COVID-19 epidemiology and rural healthcare: a survey in a Spanish village

Rodríguez-del-Río,

Barroso,

Fernández-de-Mera

et al. 2023

Epidemiol. Infect.

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We used primary care data to retrospectively describe the entry, spread, and impact of COVID-19 in a remote rural community and the associated risk factors and challenges faced by the healthcare team. Generalized linear models were fitted to assess the relationship between age, sex, period, risk group status, symptom duration, post-COVID illness, and disease severity. Social network and cluster analyses were also used. The first six cases, including travel events and a social event in town, contributed to early infection spread. About 351 positive cases were recorded and 6% of patients experienced two COVID-19 episodes in the 2.5-year study period. Five space–time case clusters were identified. One case, linked with the social event, was particularly central in its contact network. The duration of disease symptoms was driven by gender, age, and risk factors. The probability of suffering severe disease increased with symptom duration and decreased over time. About 27% and 23% of individuals presented with residual symptoms and post-COVID illness, respectively. The probability of developing a post-COVID illness increased with age and the duration of COVID-associated symptoms. Carefully registered primary care data may help optimize infection prevention and control efforts and upscale local healthcare capacities in vulnerable rural communities.

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Serum biomarkers for nutritional status as predictors in COVID-19 patients before and after vaccination

Cited by 12 publications

References 73 publications

Relationship between sarcopenia and cachexia with prognostic markers of middle-aged and older inpatients with COVID-19: a case-control study

Relationship between sarcopenia and cachexia with prognostic markers of middle-aged and older inpatients with COVID-19: a case-control study

Relationship between sarcopenia and cachexia with prognostic markers of middle-aged and older inpatients with COVID-19: a case–control study

COVID-19 epidemiology and rural healthcare: a survey in a Spanish village

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