“…3,4 This is particularly relevant because as individuals age, they undergo significant changes in body composition, 5 leading to alterations in nutritional status and an increased susceptibility to conditions such as sarcopenia, malnutrition, and frailty, which can have serious implications. [6][7][8] In recent times, the GNRI has emerged as a valuable marker of frailty in various clinical contexts, 9,10 particularly in older patients undergoing surgical procedures, where it has demonstrated significant prognostic value in predicting postoperative outcomes. These findings are noteworthy as they underscore the dual complexity of this seemingly simple index, which not only assesses nutritional risk but also correlates with adverse outcomes.…”