Serosurvey of anti-treponema pallidum (syphilis), anti-hepatitis C virus and anti-HIV antibodies in homeless persons of São Paulo city, southeastern Brazil

Felipetto, Laís Giuliani; Teider-Junior, Pedro Irineu; Silva, Felipe Fortino Verdan da; Couto, Anahi Chechia do; Kmetiuk, Louise Bach; Martins, Camila Marinelli; Ullmann, Leila Sabrina; Timenetsky, Jorge; Santos, Andrea Pires dos; Biondo, Alexander Welker

doi:10.1016/j.bjid.2021.101602

Cited by 2 publications

(2 citation statements)

References 23 publications

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“…Besides being the largest city in Latin America, São Paulo has been among the most multicultural cities worldwide, accounting for the largest population of migrants, immigrants, and refugees nationwide [ 37 ]. Such a scenario of social vulnerability has challenged health authorities, for example, seropositivity of anti- Treponema pallidum antibodies has been significantly higher ( P = 0.043) in immigrant persons experiencing homeless conditions [ 38 ]. Fortunately, although the homeless population was predominantly composed of 133/194 (68.6%) migrants and 134/194 (69.1%) non-white persons, both variables were not associated with toxocariasis.…”

Section: Discussionmentioning

confidence: 99%

Serosurvey of anti-Toxocara canis antibodies in people experiencing homelessness and shelter workers from São Paulo, Brazil

et al. 2022

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Background Despite being one of the most prevalent helminth parasitic zoonoses worldwide and particularly in socioeconomically vulnerable populations, toxocariasis remains to be fully investigated in persons experiencing homelessness. Accordingly, the present study has aimed to assess the seroprevalence and associated risk factors of Toxocara spp. exposure in persons experiencing homelessness and shelter workers from a day-shelter in São Paulo city, Brazil. Methods Anti-Toxocara IgG antibodies were detected by enzyme-linked immunosorbent assay (ELISA). Univariable and multivariable logistic regression models were performed to assess the risks for toxocariasis. Results Overall, anti-Toxocara IgG antibodies were detected in 89/194 (45.9%, 95% CI: 39.0–52.9%) persons experiencing homelessness, twice as high (OR = 2.2; 95% CI = 1.245–3.873; P = 0.0089) than the frequency of 22/79 (27.8%, 95% CI: 19.2–38.6) in shelter workers. College education was the only protective factor for Toxocara spp. exposure (OR: 0.23; P = 0.018) revealed by logistic regression. Conclusions Although indicating a multifactorial origin of toxocariasis, the present study has assessed a highly vulnerable population with high disease risks and premature death. Thus, the living conditions of the homeless population have influenced the high prevalence of anti-Toxocara antibodies verified here compared with domiciled shelter workers. Despite being less exposed, shelter and other outdoor workers may present an occupational risk to toxocariasis. Future studies should establish whether such environmental exposure might occur in persons experiencing homelessness in other regions worldwide. Graphical Abstract

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Section: Discussionmentioning

confidence: 99%

Serosurvey of anti-Toxocara canis antibodies in people experiencing homelessness and shelter workers from São Paulo, Brazil

et al. 2022

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“…The One Health approach herein has shown seropositive dogs with no concurrent human exposure, indicating that each pathogen may have different animal and environmental risks for causing human infection, and all should be surveyed together. In contrast, homeless persons are reportedly more exposed to diseases transmitted from human-to-human, such as sexually transmitted infections from unprotected sex and needle-sharing behavior (syphilis, HIV, and hepatitis [ 28 ], and COVID-19 [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

One health approach on serosurvey of anti-Leptospira spp. in homeless persons and their dogs in South Brazil

et al. 2022

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Serosurvey of anti-treponema pallidum (syphilis), anti-hepatitis C virus and anti-HIV antibodies in homeless persons of São Paulo city, southeastern Brazil

Cited by 2 publications

References 23 publications

Serosurvey of anti-Toxocara canis antibodies in people experiencing homelessness and shelter workers from São Paulo, Brazil

Serosurvey of anti-Toxocara canis antibodies in people experiencing homelessness and shelter workers from São Paulo, Brazil

One health approach on serosurvey of anti-Leptospira spp. in homeless persons and their dogs in South Brazil

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