Serological diagnosis of Helicobacter pylori--evaluation of four tests in the presence or absence of non-steroidal anti-inflammatory drugs.

Evaluation of a new immunochromatographic test for Helicobacter pylori IgG antibodies in elderly symptomatic patients

“…[18][19][20][21] The FlexPack HP, evaluated in our study, had a sensitivity and negative predictive value of 84% and 63%, respectively. False-positive FlexPack HP results were obtained in 16 serum or blood specimens (there was 100% agreement between the serum and the blood results).…”

Helicobacter pylori and Bleeding Duodenal Ulcer: Prevalence of the Infection and Role of Non-steroidal Anti-inflammatory Drugs

“…Furthermore, other endoscopic-based diagnostic tests (such as histology, Gram stain or culture) (7) have also been reported to have low sensitivity in patients with bleeding ulcer (17,19,20), suggesting that non-invasive methods, such as serology or urea breath test, should be used to identify H. pylori infection in these patients (24,25). Nevertheless, some studies suggest that serologic methods are less accurate in patients treated with NSAIDs (26,27), which is the case in most patients with UGIB. Some authors have reported a low sensitivity of histological methods in patients with UGIB (17,19,20,28).…”

Comparison of Serum IgA and IgG Antibodies for Detecting Helicobacter pylori Infection

“…The reported sensitivity and specificity of IgG serology is highly variable, ranging from 30% to 100% (12)(13)(14). The HM-CAP IgG, evaluated in our study, had a sensitivity, specificity, positive predictive value, and negative predictive value of 94.7, 88.0, 90.9, and 93.0%, respectively.…”