Sero-prevalence of Transfusion Transmissible Infections among Voluntary Blood Donors of Khulna Medical College Hospital

Alom, SM Tushar; Mondal, Kanak Jyoti; Tarafder, Shirin; Sonia, Farah Anjum; Chowdhury, Poritosh Kumar; Islam, Saiful

doi:10.3329/bmj.v46i2.40212

Cited by 5 publications

(6 citation statements)

References 16 publications

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“…The seroprevalence of HCV in the present study was 0.81%, which is high when compared with a study from Bangladesh 27 (0.03%). Our finding was on the lower side when compared to previous studies from Sudan 28 (1.40%), Pakistan 29 (3.26%), Kenya 30 (3.21%), and Nigeria 21 (3.6%).…”

Section: Discussioncontrasting

confidence: 80%

“…On the other hand, studies from Bangladesh 26 (0.20%), USA 35 (0.16%), Saudi Arabia 36 (0.04%), and India 32 (0.05%) reported a lower prevalence rate for syphilis in blood donors. Conversely, it is lower than 5.72% in Sudan, 27 3.1% in Nigeria, 21 and 1.9% in Tanzania. 11 …”

Section: Discussionmentioning

confidence: 77%

“…However, it is on the lower side when compared to previous studies conducted in Saudi Arabia 26 (0.13%), India 32 (0.6%), Nigeria 21 (4.2%), and Sudan (2.61%). 27 A possible reason for this lower rate of HIV infection could be a decrease in the prevalence of HIV at population level and due to enhanced effectiveness of the blood donor awareness programme in ensuring behavioural screening.…”

Section: Discussionmentioning

confidence: 99%

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First Report from Afghanistan on the Prevalence of Blood-Borne Infections: A Retrospective Cross-Sectional Multicentre Study for an Epidemiological Assessment

Hashemi¹,

Waheed²,

Saba³

et al. 2022

JBM

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Background The transfusion of blood and blood components has a significant role in healthcare services. However, it remains a possible risk factor for blood-borne infections. The present study was conducted to assess the prevalence of serological markers of common blood-borne infections among the blood donor population of Afghanistan. Methodology This was a cross-sectional study based on retrospectively collected data over a period of six years from 284 blood centres across 34 provinces of Afghanistan. Every blood donor’s sample was tested by rapid immunoassays for the serological markers of blood-borne infections namely hepatitis B surface antigen (HBsAg), anti-hepatitis C virus (anti-HCV), anti-human immunodeficiency virus 1/2 (anti-HIV1/2), and anti-Treponema pallidum (anti-TP). Results All blood donors during the study period were males. The majority of blood donations were from the family replacement category 56.93% (n = 544,568). The overall pooled prevalence of blood-borne infections was 4.36% with a comparatively higher percentage in family replacement donors 4.88%. The seropositivity for HBsAg, anti-HCV, anti-HIV1/2, and anti-TP was 2.95%, 0.81%, 0.04%, and 0.54%, respectively. Conclusion Complete reliance on voluntary blood donors and screening with quality assured highly sensitive assay is recommended to ensure blood safety in the country.

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Section: Discussioncontrasting

confidence: 80%

Section: Discussionmentioning

confidence: 77%

Section: Discussionmentioning

confidence: 99%

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First Report from Afghanistan on the Prevalence of Blood-Borne Infections: A Retrospective Cross-Sectional Multicentre Study for an Epidemiological Assessment

Hashemi¹,

Waheed²,

Saba³

et al. 2022

JBM

View full text Add to dashboard Cite

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“…The prevalence of HCV infection among blood donors in this study was 0.00%, which is slightly comparable with previous studies (0.2%) in south west Ethiopia 33 and elsewhere in the world; 0.06% in Pakistan, 34 and 0.03% in Bangladesh. 35 On the other hand, this finding is much lower than previous studies done in Nigeria (2.5%) 27 and Kenya (3.21%). 36 The wide variations of HCV sero-prevalence in different studies might be due to differences in risk behaviors such as injecting drug use and sharing objects for skin piercing between different geographical areas, use of different methods for testing, and use of different generation of ELISA test kits, having different sensitivities and specificities and use of different sample size.…”

Section: Discussionmentioning

confidence: 65%

Transfusion Transmissible Infections Among Voluntary Blood Donors at Dessie Blood Bank, Northeast Ethiopia: Cross-Sectional Study

Kebede

Getnet

Enyew

et al. 2020

IDR

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Background The prevalence of transfusion transmitted infections (TTIs) among blood donors varies across different geographical populations. Establishing the sero-prevalence of the disease among blood donors is important to informing the direction of preventive and control strategies. Objective The aim of this study was to determine the sero-prevalence of transfusion transmitted infections among voluntarily blood donors at Dessie Blood Bank, North East Ethiopia. Methods and Materials A cross-sectional study was conducted from November 10 to December 12, 2018. A total of 384 blood donors were conveniently included in this study. Socio-demographic data and other factors were collected using a pre-tested structured questionnaire. Five milliliters of venous blood was collected using a sterile test tube from each blood donor and the blood was allowed to clot; then, serum was separated by centrifugation for laboratory investigation. Serum samples from blood donors were tested by enzyme-linked immunosorbent assays (ELISA) for the presence of hepatits B surface antigen (HBsAg), and antibodies to human immunodeficiency virus (HIV-1/2), hepatits C virus (HCV), and Treponema pallidum . Logistic regression was used to explore risk factors associated with each transfusion transmissible infection. Results From a total of 384 blood donors, 24 (6.25%) of them had serological evidence for at least one infection. The overall sero-prevalence rates of HBV, HCV, HIV, and syphilis among blood donors were 4.2%, 0%, 0.26%, and 1.82%, respectively. Educational status was significantly associated with HBV infection. Multiple sexual behaviors had statistically significant association with syphilis. Conclusion In conclusion, 6.25% of blood donors still harbor transfusion transmissible infections despite recent blood donation safety improvements with the greater majority (4.2%) of cases caused by HBV infection.

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“…All positive samples were repeated 3 times before labeling as seropositive and respective blood units were discarded. All data were analyzed by Microsoft-EXCEL 2016 7 .…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Transfusion Transmissible Infections (HBV, HCV, HIV and Treponema pallidum in Volunteer Blood Donors in Shirajganj District

Hasan¹,

Shammi²,

Kabir³

2020

Bangla. J. Microbiol.

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Blood and its components are essential for life and often required to be transfused in critical health condition. However, such transfusion is reported to be associated with the risk of transfusion transmissible infections (TTIs) with notable pathogens e.g. Hepatitis B virus (HBV), Hepatitis C virus (HCV), Human immunodeficiency virus (HIV) and Treponema pallidum. These pathogens are of major public health concern especially in developing countries like Bangladesh. Increase in the number of TTIs is found to be associated with improper management of safe blood transfusion protocol (SBTP) and unethical practices. This study focuses on the prevalence of such TTIs in volunteers’ blood collected between October and December 2018 from Sakhawath Memorial and Avicina Hospitals in Shirajgong district. Prevalence rate of HIV, HBsAg, HCV and Treponema pallidum were 1.2%, 6.8%, 0.8% and 1.6%, respectively. Among the infected individuals, 75% HIV positive cases were professionals, 70% HCV infected cases wwere from other professional groups and 50% of syphilis infected were homemakers. Male donors showed higher incidence rate of HBV (65%), HCV (72%) and HIV (85%) compared to the female donors. Although the findings of the study showed prevalence of TTIs in volunteer blood donors (VBDs) at an alarming rate, most of the infected individuals were not aware of their infections and potential risk of transmission from them. It is necessary to create awareness among blood donors about possible causes of transmission and prevention of infection . Such initiative from both governmental and non-governmental organizations can help reduce TTIs among VBDs. Bangladesh J Microbiol, Volume 36 Number 2 December 2019, pp 105-109

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Sero-prevalence of Transfusion Transmissible Infections among Voluntary Blood Donors of Khulna Medical College Hospital

Cited by 5 publications

References 16 publications

First Report from Afghanistan on the Prevalence of Blood-Borne Infections: A Retrospective Cross-Sectional Multicentre Study for an Epidemiological Assessment

First Report from Afghanistan on the Prevalence of Blood-Borne Infections: A Retrospective Cross-Sectional Multicentre Study for an Epidemiological Assessment

Transfusion Transmissible Infections Among Voluntary Blood Donors at Dessie Blood Bank, Northeast Ethiopia: Cross-Sectional Study

Prevalence of Transfusion Transmissible Infections (HBV, HCV, HIV and Treponema pallidum in Volunteer Blood Donors in Shirajganj District

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