Semiquantitative histomorphometric analysis of myocardium following partial left ventriculectomy: 1‐year follow‐up

Vasiljević, Jovan; Otašević, Petar; Popović, Zoran B.; Nešković, Aleksandar N.; Vidaković, Radoslav; Popović, Zoran V.; Radovančević, Branislav; Frazier, O.H.; Gradinac, Siniša

doi:10.1016/j.ejheart.2004.09.016

Cited by 3 publications

(1 citation statement)

References 18 publications

(25 reference statements)

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“…In 2005 a study about the morphological effect in 15 patients surviving to PLV was performed a year after its completion, and it was verified that in addition to the significant reduction in the functional classes these patients presented, there were also favorable effects on myocardial structure, especially in the ventricular diameter and in the tissue quality [ 27 ] .…”

Section: Resultsmentioning

confidence: 99%

Partial left ventriculectomy: Have well-succeeded cases and innovations in the procedure been observed in the last 12 years?

Domingues¹,

Vale²,

Barbosa³

2015

Revista Brasileira De Cirurgia Cardiovascular

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OBJECTIVE In 1996, the Brazilian cardiovascular surgeon, Dr. Randas Batista, introduced a surgical technique called partial left ventriculectomy, where he admitted the possibility of reducing the diameter of the left ventricle through the sectioning of one section of its wall. After the publication of this study, thousands of case reports and procedure analysis have been published, and due to several disappointing results, many doctors and institutions failed to execute it. As the main objective of this study, stands out the search for success cases of ventriculectomy in the last 12 years and if during this period it was achieved some significant development in this procedure that allows obtaining lower mortality rate postoperatively.METHODS Systematic review of indexed scientific literature over the past 12 years and the term "Partial Left Ventriculectomy".RESULTS There has been a considerable number of reported successful cases and highly significant findings in regard to determining the most suitable region for the section, proper selection of the patients indicated to the procedure, including the influence of the coronary artery anatomy in the nomination procedure and the need for preservation of ventricular geometry to ensure better quality of ventricular contractions after the sectioning.CONCLUSION This surgical procedure has been successfully performed, mainly in Japan, improvements in its efficiency were found and the need for a mathematical modeling of the slice to be severed is a prominent factor in many studies.

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Section: Resultsmentioning

confidence: 99%

Partial left ventriculectomy: Have well-succeeded cases and innovations in the procedure been observed in the last 12 years?

Domingues¹,

Vale²,

Barbosa³

2015

Revista Brasileira De Cirurgia Cardiovascular

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Clinical significance of endomyocardial biopsy in conjunction with cardiac magnetic resonance imaging to predict left ventricular reverse remodeling in idiopathic dilated cardiomyopathy

et al. 2016

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Endomyocardial biopsy (EMB) and cardiac magnetic resonance (CMR) are useful modalities to study the characteristics of myocardial tissue. However, the prognostic impact of both diagnostic tools to predict subsequent left ventricular reverse remodeling (LVRR) has not been well elucidated. A total of 187 consecutive patients with idiopathic dilated cardiomyopathy (IDCM) who were treated by optimal pharmacotherapy (OPT) and underwent EMB of the LV wall were investigated. The myocardial specimens were semiquantitatively evaluated measuring cardiomyocyte degeneration (CD), interstitial fibrosis (IF), and hypertrophy. In addition, late gadolinium enhancement (LGE)-CMR was performed in 78 (48 %) patients. Seventy-eight (48 %) patients developed LVRR, defined as a ≥10 % increase in LV ejection fraction with a ≥10 % decrease in indexed LV end-diastolic dimension at 12 months after OPT. Multivariate regression analysis revealed that CD (P = 0.003), but not IF (P = 0.320), was an independent predictor of LVRR. In the patients with not only EMB but also CMR, the CD score and LGE area were independent predictors of LVRR (odds ratios/P values 0.268/0.010, 0.855/<0.001, respectively). The patients with mild CD and negative LGE had a better achievement rate of LVRR than those with severe CD and positive LGE (74 vs. 19 %). A combination of CD score on EMB and LGE-CMR is useful to predict subsequent LVRR in IDCM patients.

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Impact of Autophagy on Prognosis of Patients With Dilated Cardiomyopathy

Kanamori

Yoshida

Naruse

et al. 2022

Journal of the American College of Cardiology

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Semiquantitative histomorphometric analysis of myocardium following partial left ventriculectomy: 1‐year follow‐up

Cited by 3 publications

References 18 publications

Partial left ventriculectomy: Have well-succeeded cases and innovations in the procedure been observed in the last 12 years?

Partial left ventriculectomy: Have well-succeeded cases and innovations in the procedure been observed in the last 12 years?

Clinical significance of endomyocardial biopsy in conjunction with cardiac magnetic resonance imaging to predict left ventricular reverse remodeling in idiopathic dilated cardiomyopathy

Impact of Autophagy on Prognosis of Patients With Dilated Cardiomyopathy

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