A 63-year-old-woman with history of dispneia, palpitation and precordial discomfort was examined. The physical examination failed to reveal abnormalities. The diagnosis of cardiac tumor was accomplished with the help of bidimensional echocardiography, computadorized tomography and hemodinamic study. The operation was completed and the diagnosis of myxoma was confirmed by histopathologic study. The post-operative regarding the diagnosis was done in the present report, including the development of pleural effusion possibly related to myxoma.Descriptors: Myxoma/diagnosis. Myxoma/ surgery. Heart neoplasms/surgery. Myxoma/ complications.
Resumo
VALE, MP ET AL -Giant myxoma in the left atrium -Case reportRev Bras Cir Cardiovasc 2008; 23(2): 276-278
The main aim of this study was the formula application of the superficial area of a truncated prolate spheroid (TPS) in Cartesian coordinates in obtaining a cardiac parameter that is not so much discussed in literature, related to the left ventricle (LV) surface area of the human heart, by age and sex. First we obtain a formula for the area of a TPS. Then a simple mathematical model of association of the axes measures of a TPS with the axes of the LV is built. Finally real values of the average dimensions of the humans LV are used to measure surface areas approximations of this heart chamber. As a result, the average superficial area of LV for normal patients is obtained and it is observed that the percentage differences of areas between men and women and their consecutive age groups are constant. A strong linear correlation between the obtained areas and the ventricular volumes normalized by the body areas was observed. The obtained results indicate that the superficial area of the LV, besides enabling a greater knowledge of the geometrical characteristics of the human LV, may be used as one of the normality cardiac verification criteria and be useful for medical and biological applications.
OBJECTIVE In 1996, the Brazilian cardiovascular surgeon, Dr. Randas Batista, introduced a
surgical technique called partial left ventriculectomy, where he admitted the
possibility of reducing the diameter of the left ventricle through the sectioning
of one section of its wall. After the publication of this study, thousands of case
reports and procedure analysis have been published, and due to several
disappointing results, many doctors and institutions failed to execute it. As the
main objective of this study, stands out the search for success cases of
ventriculectomy in the last 12 years and if during this period it was achieved
some significant development in this procedure that allows obtaining lower
mortality rate postoperatively.METHODS Systematic review of indexed scientific literature over the past 12 years and the
term "Partial Left Ventriculectomy".RESULTS There has been a considerable number of reported successful cases and highly
significant findings in regard to determining the most suitable region for the
section, proper selection of the patients indicated to the procedure, including
the influence of the coronary artery anatomy in the nomination procedure and the
need for preservation of ventricular geometry to ensure better quality of
ventricular contractions after the sectioning.CONCLUSION This surgical procedure has been successfully performed, mainly in Japan,
improvements in its efficiency were found and the need for a mathematical modeling
of the slice to be severed is a prominent factor in many studies.
ABSTRACT. This study describes the development of equipment capable of transporting decellularization fluid through an organ by perfusion to create an in vitro acellular scaffold that maintains the three-dimensional architecture of the organ. The equipment was designed to be compatible with several existing decellularization protocols and can be used to modify the flow rate, perfusion pressure, and temperature in each decellularization protocol as well as the technique of cannulation of the organ in a controlled manner. The device was tested with chicken hearts and efficiently accomplished decellularization using the perfusion method. Further amendments can be made to improve the efficiency of the decellularization of diverse organs. It is expected that this equipment will aid in the characterization and improvement of the decellularization process and may have future applications in the process of recellularization of different organs.Keywords: decellularization; cardiac bioengineering; biomaterials; perfusion process; heart decellularization Desenvolvimento de equipamento para decelularização pelo método de perfusão RESUMO. O presente estudo descreve o desenvolvimento de um equipamento capaz de transportar o fluido de decelularização através do órgão inteiro, por perfusão, para criar uma estrutura acelular in vitro que mantém a arquitetura tridimensional completa do órgão. O equipamento foi concebido ser compatível com vários protocolos de decelularização existentes e pode ser utilizado para modificar a vazão, a pressão e a temperatura de perfusão em cada protocolo, bem como a técnica de canulação do órgão de uma forma controlada. O dispositivo foi testado com corações de galinha e executou eficientemente o protocolo de decelularização, utilizando o método de perfusão. Outras alterações podem ser feitas para melhorar a eficiência da decelularização em diversos órgãos. Espera-se que este equipamento auxilie na caracterização e melhoria do processo de decelularização além de possibilitar futuras aplicações no processo de recelularização de diferentes órgãos.Palavras-chave: decelularização; bioengenharia cardíaca; biomateriais; processo de perfusão; decelularização de coração.
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