Self‐Assembly and Applications of Biomimetic and Bioactive Peptide‐Amphiphiles

Kokkoli, Efrosini; Mardilovich, Anastasia; Wedekind, Alison; Rexeisen, Emilie L.; Garg, Ashish; Craig, Jennifer A.

doi:10.1002/chin.200742249

Cited by 16 publications

(21 citation statements)

References 1 publication

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“…The structural characteristics and physico--chemical properties of these assemblies can be modified by changing the segments of amphiphilic molecules. The hydrophobicity can be tuned with the use of different alkyl chain lengths and the solubility or responsive behaviour of these materials can be controlled with the appropriate number of charged AA [235,237].…”

Section: 5--self--assembled Systems Of Peptide--amphiphilesmentioning

confidence: 99%

Self-assembling polymer systems for advanced treatment of cancer and inflammation

Palao-Suay

Gómez‐Mascaraque

Aguilar

et al. 2016

Progress in Polymer Science

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Section: 5--self--assembled Systems Of Peptide--amphiphilesmentioning

confidence: 99%

Self-assembling polymer systems for advanced treatment of cancer and inflammation

Palao-Suay

Gómez‐Mascaraque

Aguilar

et al. 2016

Progress in Polymer Science

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“…An important class of amphiphilic peptides is comprised of a peptidic hydrophilic head and alkyl/lipid chains as the hydrophobic tail. Several examples of this class have been published for their bioactive applications [11].…”

Section: Amphiphilic Peptidesmentioning

confidence: 99%

Constructing biomaterials using self-assembling peptide building blocks

Chen

2010

Front. Mater. Sci. China

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Molecular self-assembly is ubiquitous in nature and has recently emerged as a new bottom-up approach in constructing biomaterials. Synthetic peptides assemble through specific molecular recognition and form diverse nanostructures. The resulting versatile peptide selfassemblies may be used in a wide range of biological and medical applications. Examples of two self-assembling peptide systems are presented and techniques for selfassembly control are discussed.

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“…For drug delivery applications, specific targeting with desired sites is very important for the nanocarriers to deliver or transport the drugs efficiently [132]. For this purpose, peptides self-assembled nanostructures have many advantages such as easier modification properties and tunable design of the recognition motifs.…”

Section: Targeted Drug Deliverymentioning

confidence: 99%

Peptide Self-Assembled Nanostructures for Drug Delivery Applications

Fan

Shen

et al. 2017

Journal of Nanomaterials

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Peptide self-assembled nanostructures are very popular in many biomedical applications. Drug delivery is one of the most promising applications among them. The tremendous advantages for peptide self-assembled nanostructures include good biocompatibility, low cost, tunable bioactivity, high drug loading capacities, chemical diversity, specific targeting, and stimuli responsive drug delivery at disease sites. Peptide self-assembled nanostructures such as nanoparticles, nanotubes, nanofibers, and hydrogels have been investigated by many researchers for drug delivery applications. In this review, the underlying mechanisms for the self-assembled nanostructures based on peptides with different types and structures are introduced and discussed. Peptide self-assembled nanostructures associated promising drug delivery applications such as anticancer drug and gene drug delivery are highlighted. Furthermore, peptide self-assembled nanostructures for targeted and stimuli responsive drug delivery applications are also reviewed and discussed.

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Self‐Assembly and Applications of Biomimetic and Bioactive Peptide‐Amphiphiles

Cited by 16 publications

References 1 publication

Self-assembling polymer systems for advanced treatment of cancer and inflammation

Self-assembling polymer systems for advanced treatment of cancer and inflammation

Constructing biomaterials using self-assembling peptide building blocks

Peptide Self-Assembled Nanostructures for Drug Delivery Applications

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