Selenium-Dependent Regulation of Oxidative Stress and Immunity in Periparturient Dairy Cattle

Sordillo, Lorraine M.

doi:10.1155/2013/154045

Cited by 126 publications

(109 citation statements)

References 74 publications

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“…Pregnancy in dairy cows induces oxidative stress that can be a significant underlying factor leading to dysfunctional host immune and inflammatory responses that can increase the incidence and severity of infectious diseases (Sordillo 2013). The peripartal period is one of the most stressful periods in the life of dairy cows.…”

Section: Discussionmentioning

confidence: 99%

Oxidative stress and antioxidant status in dairy cows during prepartal and postpartal periods

et al. 2015

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The aim of the present study was to evaluate the indicators of oxidative stress (malondialdehyde [MDA]) and antioxidant status (ferric reducing ability of plasma [FRAP]; superoxide dismutase [SOD]; glutathione peroxidase [GSH-Px]; selenium [Se]; vitamin E) in dairy cows of the Slovak Pied cattle from 3 weeks before parturition to 9 weeks after parturition. The mean MDA concentration was significantly (P < 0.001) higher in the cows 1 week after calving compared to the cows 3, 6, and 9 weeks after calving. The lowest mean FRAP value was found in the cows 3 weeks after parturition. The SOD activities were increased during the whole monitored time (ANOVA, P < 0.001). A significant (P < 0.05) decrease of GSH-Px activities was recorded in the cows 1 week after calving compared to the weeks 6 and 9 after calving. Statistical multiple comparison test showed no significant changes in Se between the examined groups. The lowest mean vitamin E concentration was found in the first week after parturition. Significantly positive correlations (P < 0.05) were recorded between Se and vitamin E (r = 0.897), SOD and GSH-Px (r = 0.903), while Se and GSH-Px had no significantly positive correlation (r = 0.520). Significant changes between MDA and indicators of oxidative stress (SOD, GSH-Px, vitamin E) confirm that during parturition and onset of lactation, oxidative stress occurs in dairy cows. Exposure of peripartal cows to oxidative stress may cause an increased incidence of metabolic diseases.

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Section: Discussionmentioning

confidence: 99%

Oxidative stress and antioxidant status in dairy cows during prepartal and postpartal periods

et al. 2015

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“…Possibly, suppressed immunity around parturition 132 facilitated dissemination of M. bovis. In the same way the low selenium levels of cow 3 and 4 might 133 have played an additional role in the illness, as this deficiency has been linked to a lowered 134 periparturient immunity level (Sordillo, 2013). …”

Section: Bacteriology and Strain Typing 108mentioning

confidence: 99%

A new predilection site of Mycoplasma bovis: Postsurgical seromas in beef cattle

Gille

Pilo²,

Valgaeren

et al. 2016

Veterinary Microbiology

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“…Selenium (Se) is an essential trace mineral in animals that is required to maintain normal physiological functions and provides a significant dietary source of antioxidant defenses (Sordillo, 2013). It is obtained by animals as components of the diet and its transplacental transfer is an important factor for their offspring.…”

Section: Introductionmentioning

confidence: 99%

The effect of organic selenium in feeding of ewes in late pregnancy on selenium transfer to progeny

et al. 2017

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-The objective of this study was to determine the effect of supplemented organic selenium at different levels to concentrate feed of Norduz ewes in late pregnancy on maternal serum, placenta, colostrum, and offspring serum concentrations. This study was conducted using two-year-old 35 Norduz ewes. Ewes were randomly assigned to one of three dietary treatments for 57 days prepartum and at the seven days postpartum. Group 1 was fed a standard pregnant sheep concentrate basal diet without any additional Se supplement (control). Experiment groups were fed diets supplemented with 0.150 mg/kg, 0.300 mg/kg, and 0.450 mg/kg organic selenium to the same basal diet. Results showed that addition of selenium to gestating ewe diets increased Se in serum after one week of feeding. Ewes supplemented with 0.300 and 0.450 mg/kg Se had increased placenta, serum, and colostrum Se levels compared with those fed the control diet (P<0.05). There was a strong positive correlation between placental and serum Se concentration in ewes. Colostrum Se increased linearly with dietary Se in the treatment groups. At birth, lamb serum Se ranged from 48.96 ng/mL to 195.52 ng/mL and was affected by the Se concentration of the ewe diets, which indicated placenta transfer of selenium from the dam. As selenium level increased in basal diet, an upward trend was observed in maternal free thyroxine concentration. Likewise, serum free triiodothyronine, free thyroxine, and immunoglobulin G concentrations of lambs from the three treatment groups were significantly greater than of the control lambs. As a result, selenium supplementation was important for maintaining Se and immunoglobulin G concentration in placenta, serum, and colostrum in ewes.

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Selenium-Dependent Regulation of Oxidative Stress and Immunity in Periparturient Dairy Cattle

Cited by 126 publications

References 74 publications

Oxidative stress and antioxidant status in dairy cows during prepartal and postpartal periods

Oxidative stress and antioxidant status in dairy cows during prepartal and postpartal periods

A new predilection site of Mycoplasma bovis: Postsurgical seromas in beef cattle

The effect of organic selenium in feeding of ewes in late pregnancy on selenium transfer to progeny

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