Selective serotonin reuptake inhibitors in sewage influents and effluents from Tromsø, Norway

Vasskog, Terje; Berger, Urs; Samuelsen, Per-Jostein; Kallenborn, Roland; Jensen, Einar

doi:10.1016/j.chroma.2006.02.091

Cited by 118 publications

(74 citation statements)

References 31 publications

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“…This pharmaceutical was also detected in surface waters [23,188], groundwaters [28] and drinking water [32]. Other SSRIs, such as fluvoxamine, sertraline and paroxetine have also been detected in STP influents and effluents [186][187][188] as well as seawater (Nor-way) [187]. Antidepressants were detected at low concentrations (ng L −1 ) which may not represent isolated threats to non-target organisms when considering the respective contribution.…”

Section: Antidepressantsmentioning

confidence: 98%

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Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment

Santos

Araújo

Fachini

et al. 2010

Journal of Hazardous Materials

1,284

533

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Pharmaceuticals are biologically active and persistent substances which have been recognized as a con-tinuing threat to environmental stability. Chronic ecotoxicity data as well as information on the current distribution levels in different environmental compartments continue to be sparse and are focused on those therapeutic classes that are more frequently prescribed and consumed. Nevertheless, they indicate the negative impact that these chemical contaminants may have on living organisms, ecosystems and ultimately, public health. This article reviews the different contamination sources as well as fate and both acute and chronic effects on nontarget organisms. An extensive review of existing data in the form of tables, encompassing many therapeutic classes is presented.Keywords: Pharmaceuticals, Sources, Environmental fate, Ecotoxicological effects

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Section: Antidepressantsmentioning

confidence: 98%

“…Fluoxetine is a typical example, being detected in STP influents at concentrations of 0.4-18.7 ng L −1 and in effluents in the lower range of 0.12-8.4 ng L −1 [186][187][188]. This pharmaceutical was also detected in surface waters [23,188], groundwaters [28] and drinking water [32].…”

Section: Antidepressantsmentioning

confidence: 98%

Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment

Santos

Araújo

Fachini

et al. 2010

Journal of Hazardous Materials

1,284

533

View full text Add to dashboard Cite

show abstract

“…Many SSRIs are persistent in the environment (Kwon and Armbrust, 2005) and pass through sewage treatment plants (STPs) with very little or no degradation taking place (Vasskog et al, 2006). Citalopram and other SSRIs are frequently found in STP effluents and have been reported in concentrations between 0.02 and 840 µg/l (Larsson et al, 2007;Vasskog et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

Environmentally relevant concentrations of citalopram partially inhibit feeding in the three-spine stickleback (Gasterosteus aculeatus)

et al. 2015

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PostprintThis is the accepted version of a paper published in Aquatic Toxicology. This paper has been peerreviewed but does not include the final publisher proof-corrections or journal pagination.Citation for the original published paper (version of record):Kellner, M., Porseryd, T., Porsch-Hallstrom, I., Hansen, S., Olsén, H. (2015) Environmentally relevant concentrations of citalopram partially inhibit feeding in the three-spine stickleback (Gasterosteus aculeatus).Aquatic Toxicology,[158][159][160][161][162][163][164][165][166][167][168][169][170] http://dx.doi.org/10.1016/j.aquatox. 2014.11.003 Access to the published version may require subscription. N.B. When citing this work, cite the original published paper. NOTICE: this is the author's version of a work that was accepted for publication in Aquatic Toxicology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Aquatic Toxicology, Vol. 158,[165][166][167][168][169][170] Abstract Selective Serotonin Re-uptake Inhibitors (SSRI) are mood-altering, psychotropic drugs commonly used in the treatment of depression and other psychological illnesses. Many of them are poorly degraded in sewage treatment plants and enter the environment unaltered. In laboratory studies, they have been demonstrated to affect a wide range of behaviours in aquatic organisms. In this study we investigated the effect of a three week exposure of 0.15 and 1.5 µg/l of the SSRI citalopram dissolved in the ambient water on the feeding behaviour in three-spine stickleback (Gasterosteus aculeatus). Feeding, measured as the number of attacks performed on a piece of frozen bloodworms during a 10 minute period, was reduced by 40-60% in fish exposed to both 0.15 and 1.5 µg/l citalopram. The effects of the environmentally relevant dose 0.15 µg/l on feeding, an important fitness characteristic, suggests that the ecological significance of environmental SSRI exposure may be pronounced.

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“…Esses contaminantes apresentam grande diversidade de natureza química e provém das mais variadas fontes, tais como fármacos de uso humano [1][2][3] ou animal 4 e produtos de limpeza e de higiene pessoal, [5][6][7] os quais são introduzidos no meio ambiente via esgoto doméstico, seja ele tratado ou não.…”

Section: Introductionunclassified

Caracterização de contaminantes presentes em sistemas de tratamento de esgotos, por cromatografia líquida acoplada à espectrometria de massas tandem em alta resolução

Leite¹,

Afonso²,

Aquino³

2010

Quím. Nova

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Selective serotonin reuptake inhibitors in sewage influents and effluents from Tromsø, Norway

Cited by 118 publications

References 31 publications

Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment

Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment

Environmentally relevant concentrations of citalopram partially inhibit feeding in the three-spine stickleback (Gasterosteus aculeatus)

Caracterização de contaminantes presentes em sistemas de tratamento de esgotos, por cromatografia líquida acoplada à espectrometria de massas tandem em alta resolução

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