Selective recognition of Cu (II) and Fe (III) using a pyrene based chemosensor

Structure‐Property Correlation of C10‐(H)‐Arylated‐N‐(pyren‐1‐yl)‐picolinamide Regioisomers towards Cu2+ and Fe3+ Sensing

“…In the present work the LODs obtained are in the range of micromolar which are appreciable and at par with other pyrene sensors (for Cu 2 + and Fe 3 + ) and the values are well below the recommended limits of WHO. [34] Binding constants are in the reasonable range of 10 4 -10 5 M À 1 which compares well with other pyrene sensors for Cu 2 + and Fe and Fe 3 + ) where each of the two molecules act as bidentate chelating ligands to coordinate the metals, compounds 1 a, 1 b show 1 : 1 binding with metals and lead to fluorescence quenching. On the other hand, 2 a and 2 b form 1 : 1 complex with metals and most likely two of such complexes subsequently orient in a favorable way (C-10 substitutions of two molecules pointing away from each other) that lead to static or dynamic excimers.…”

“…[29] Pyrene sensors have been efficiently utilized to sense metal ions such as Cu 2 + and Fe 3 + that are ubiquitious in biological systems and play pivotal roles in metabolic processes. [12,[31][32][33][34][35][36][37][38][39][40][41][42] Cu 2 + is an integral part of several metalloenzymes and proteins while Fe 3 + plays paramount roles in several enzymatic reactions, oxygen transport and cellular metabolism. Cu 2 + deficiency leads to cardiovascular diseases, Menkes disease, Cancer while excess Cu 2 + leads to Alzheimer's and other serious conditions.…”

A brief review on novel pyrene based fluorometric and colorimetric chemosensors for the detection of Cu2+

“…Similarly, quenching is promoted by paramagnetic Cu 2+ ions for its heavy atom effect in a pyrene-based dipicolylamine derivative sensor 43. 113 The compound 43 selectively recognized Cu 2+ and Fe 3+ over the other metal cations Ni 2+ , Mg 2+ , Cd 2+ , Hg 2+ , Na + , K + , Ca 2+ , Co 2+ , Cr 3+ , Pb 2+ and Zn 2+ . Upon treatment of Cu 2+ ions, sensor 43 exhibited well-defined absorption bands in MeOH solution in which a newly appeared band at 660 nm with red shifted peaks at 290, 333 and 358 nm were observed owing to the d-d transition of Cu(II).…”

Crown‐Ether Type Chemosensor for the Determination of Fe3+/2+ by a Colorimetric Method

“…17,18 Therefore, it is highly needed to develop convenient and efficient tools for detecting iron. [19][20][21] The ways to detect iron have been developed continuously, 22,23 such as electrochemical methods, 24,25 inductively coupled plasma, 26,27 atomic absorption, [28][29][30] and absorptive stripping voltammetry. 31,32 However, these methods have some disadvantages.…”