Selective intra-arterial Y-90 microsphe

Lacin, Seda; Küçük, Özlem; Öz, İlker; Bilgiç, Sadık

doi:10.4318/tjg.2011.0164

Cited by 6 publications

(1 citation statement)

References 12 publications

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“… 1 , 4 Radioembolization is a promising but yet investigational option for these patients. 5 A standard systemic treatment has not been established for advanced HEH. Previous literature highlights single case reports of patients treated with several anti-cancer agents, but case series or phase II clinical trials are lacking.…”

Section: Introductionmentioning

confidence: 99%

Malignant Epithelioid Hemangioendothelioma of the Liver Successfully Treated with Sorafenib

2012

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Hepatic epithelioid hemangioendothelioma (HEH) is a rare disease of unknown etiology for which a standard systemic treatment has not been established. The common expression of vascular endothelial growth factor (VEGF) and its receptor in HEH provide a rationale for the reported use of antiangiogenic drugs, including bevacizumab, lenalidomide and thalidomide. We report a case of a young male patient with HEH who was treated with sorafenib for almost 2 years. Sorafenib was used instead of other VEGF inhibitors due to its convenient oral route, its dual antiangiogenic and antiproliferative activity, and its favorable safety profile. Sorafenib therapy resulted in durable stabilization with progressive calcification of liver tumors and minor but stable response of lung lesions.

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Section: Introductionmentioning

confidence: 99%

Malignant Epithelioid Hemangioendothelioma of the Liver Successfully Treated with Sorafenib

2012

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Complete disappearance of uptake of FDG in the multifocal liver hemangioendothelioma after radioembolization therapy using yttrium-90 microspheres

et al. 2012

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Hemangioendothelioma (HE) is an intermediate grade tumor that originates from vascular endothelium. It is rarely encountered in the liver as multifocal lesions. In the treatment of the hepatic HE, surgical resection, chemotherapy, interferon-alpha 2 therapy and liver transplantation have been described in the literature. Intra-arterial radioembolization therapy with yttrium-90 microsphere is an advanced and promising technique in the treatment of hepatic multifocal HEs. In this report, we aimed to present pre- and post-treatment radio-nuclear imaging features and to discuss radioembolization technique in a 56-year-old patient with multifocal liver HE.

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A rare case of intravascular epithelioid hemangioendothelioma of the cephalic vein treated with surgery and postoperative radiation therapy: a case report and review of the literature

et al. 2015

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IntroductionEpithelioid hemangioendothelioma (EHE) is a rare endothelial tumor with an intermediate grade of malignancy. Few cases of primary vascular hemangioendothelioma have been described in the literature. Surgery is the treatment of choice, but radiation therapy and chemotherapy should also be considered in particular cases.Case presentationWe present the case of a 44-year-old Caucasian woman affected by EHE of the cephalic vein, treated by complete surgical removal of the mass and postoperative local radiation therapy. At 5-year follow-up, our patient is alive, with no signs of local or distant relapse and with no late radiation-related effects.ConclusionsPostoperative radiotherapy may play a role in cases in which tumor margins are close or cannot be assessed or when high-risk features are present.

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Selective intra-arterial Y-90 microsphe

Cited by 6 publications

References 12 publications

Malignant Epithelioid Hemangioendothelioma of the Liver Successfully Treated with Sorafenib

Malignant Epithelioid Hemangioendothelioma of the Liver Successfully Treated with Sorafenib

Complete disappearance of uptake of FDG in the multifocal liver hemangioendothelioma after radioembolization therapy using yttrium-90 microspheres

A rare case of intravascular epithelioid hemangioendothelioma of the cephalic vein treated with surgery and postoperative radiation therapy: a case report and review of the literature

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