Complete disappearance of uptake of FDG in the multifocal liver hemangioendothelioma after radioembolization therapy using yttrium-90 microspheres

Abstract

Hemangioendothelioma (HE) is an intermediate grade tumor that originates from vascular endothelium. It is rarely encountered in the liver as multifocal lesions. In the treatment of the hepatic HE, surgical resection, chemotherapy, interferon-alpha 2 therapy and liver transplantation have been described in the literature. Intra-arterial radioembolization therapy with yttrium-90 microsphere is an advanced and promising technique in the treatment of hepatic multifocal HEs. In this report, we aimed to present pre- and post-treatment radio-nuclear imaging features and to discuss radioembolization technique in a 56-year-old patient with multifocal liver HE.

Clinical Results of Transarterial Radioembolization (TARE) with Holmium-166 Microspheres in the Multidisciplinary Oncologic Treatment of Patients with Primary and Secondary Liver Cancer

“…The third patient with fast liver function deterioration was the woman with hemangioendothelioma of the liver (patient #16, tumor load 58%). The treatment was indicated because of limited alternatives and a favorable result described in the literature, where a patient with the same diagnosis was successfully treated with 90 Y-TARE [26]. We decided to use 166 Ho microspheres, because of the shorter half-life and potentially faster onset of action.…”

Irreversible Electroporation as a Valid Treatment Option for Hepatic Epithelioid Hemangioendothelioma: An International Multicenter Experience

“…A 3-year OS of 82% was found following transarterial chemoembolization in twelve patients [14]. Karaman et al showed complete disappearance of FDG-uptake after Y90 transarterial radioembolization of HEHE in a case report [15]. Irreversible electroporation (IRE) has been successful in a diverse array of clinical applications [16].…”