2020
DOI: 10.1016/j.ica.2020.119696
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Selective detection of gasotransmitters using fluorescent probes based on transition metal complexes

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Cited by 24 publications
(16 citation statements)
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“… 204 For more detail on the structures and mechanism of action of these probes, the reader is referred to a recent review which summarizes the detection of HNO and other gasotransmitters using these fluorescent tools. 205 …”
Section: Hno Detection Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“… 204 For more detail on the structures and mechanism of action of these probes, the reader is referred to a recent review which summarizes the detection of HNO and other gasotransmitters using these fluorescent tools. 205 …”
Section: Hno Detection Methodsmentioning
confidence: 99%
“…204 For more detail on the structures and mechanism of action of these probes, the reader is referred to a recent review which summarizes the detection of HNO and other gasotransmitters using these fluorescent tools. 205 In summary, the biological compatibility shown by fluorescent probes and electrochemical sensors give them an advantage for performing in vivo measurements, while MIMS requires the use of complementary techniques to ensure the unequivocal detection of HNO. On the other hand, the fact that most of the fluorogenic probes are based on the one-electron reducing nature of HNO can lead to possible interferences from biological reducing agents such as thiols or ascorbate.…”
Section: 22mentioning
confidence: 99%
“…Therefore, it is possible to design transition metal-based fluorescent probes to recognize biological macromolecules tagged with isocyanides through their coordination. Although there is no report on such applications yet, there are many related researches to detect carbon monoxides with transition metal-derived fluorescent probes ( Alcarazo et al, 2009 ; Yuan et al, 2013 ; Kos and Plenio, 2015 ; Alday et al, 2020 ). As isoelectronic with carbon monoxide ( Figure 8A ), isocyanide may also be used as a ligand which can be recognized by such fluorescent probes to achieve the non-covalent fluorescent labeling of biomacromolecules ( Figure 8B ).…”
Section: Strategy 3: Isocyanide As a Coordination Ligand For Transition Metalsmentioning
confidence: 99%
“…2 Transition metal complexes have sparked interest due to their potential applications in antitumor drugs. 3,4 In organisms, DNA is the main genetic material and the carrier of genetic information. 5 It can store and transmit genetic information.…”
Section: Introductionmentioning
confidence: 99%