Selection of vaccine strains for serotype O foot-and-mouth disease viruses (2007–2012) circulating in Southeast Asia, East Asia and Far East

Mahapatra, Mana; Upadhyaya, Sasmita; Aviso, Sharie; Babu, A. Giridhar; Hutchings, G.; Parida, Satya

doi:10.1016/j.vaccine.2017.10.099

Cited by 40 publications

(44 citation statements)

References 43 publications

(52 reference statements)

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“…The role of nt and aa substitutions in virulence and/ or immunity response needs more investigation. The increased number of detected substitutions indicates the presence of many serotypes and subtypes that increase the potential for genetic recombination and creation of new variant strains [28] . Continued studies by next generation sequencing are recommended for the detection of new subtypes, tracking the source of infection, and updates in control strategy and vaccination.…”

Section: Discussionmentioning

confidence: 99%

Outbreaks of foot and mouth disease in Egypt: Molecular epidemiology, evolution and cardiac biomarkers prognostic significance

Sobhy

Bayoumi

Mor

et al. 2018

International Journal of Veterinary Science and Medicine

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Foot and mouth disease virus (FMDV) was isolated from sloughed tongue epithelium of Egyptian cattle presenting with mouth lesions and ropy salivation in two Egyptian governorates (El-Fayoum and Dakahlia). The virus was isolated in Madin-Darby bovine kidney (MDBK) cells and identified by reverse transcription-polymerase chain reaction (RT-PCR). The complete genome was obtained by next generation sequencing. The strains isolated from El-Fayoum and Dakahlia were serotype A and O, respectively and both isolates had identity with the previously reported Egyptian strains. This study reports successive outbreaks of FMDV that occurred in Egypt during 2015–2016 and describes the dynamics of two outbreaks in addition to the use of cardiac biomarkers in the diagnosis of FMD-related myocarditis in calves and its clinical relevance. Serum cardiac troponin1 (cTn I) and creatinine kinase myocardial band (CK-MB) were measured. Mean serum cardiac troponin1 (cTn I) showed significant increase (P < 0.001) in FMDV-infected calves. The increase in fatal and recovered cases was (2.794 ± 0.502 ng/mL) and (1.196 ± 0.443 ng/mL), respectively, compared to the healthy control cases (0.014 ± 0.002 ng/mL). Thus, the serum cTn-I successfully diagnosed FMD-associated myocarditis in calves but not prognostic for the fatal cases. The FMDV sequences described in this study should further help in studying FMDV endemicity in Egypt, tracking the source of infection, selection of control strategies and vaccine updates. The study also determines the clinical relevance of cardiac biomarkers in diagnosis of FMDV-related myocarditis in infected calves.

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Section: Discussionmentioning

confidence: 99%

Outbreaks of foot and mouth disease in Egypt: Molecular epidemiology, evolution and cardiac biomarkers prognostic significance

Sobhy

Bayoumi

Mor

et al. 2018

International Journal of Veterinary Science and Medicine

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“…Vaccination was not carried out in any of the goat and mixed farms, meaning that there is no clear evidence about the effectiveness of the vaccines utilized in the current outbreak. Vaccine match tests against isolates of Ind2001d sublineage showed that the O/PanAsia‐2 and O/IND/R2/75 vaccines matched well with the Ind2001d sublineage isolates (Mahapatra et al, , ). However, vaccine match tests between the O/PanAsia‐2 vaccine strain used in Jordan and the O/JOR/1/2017 isolate have not yet been carried out.…”

Section: Discussionmentioning

confidence: 99%

First detection of foot‐and‐mouth disease virus O/ME‐SA/ Ind2001e sublineage in Jordan

Ababneh

Hananeh

Ismail

et al. 2019

Transbound Emerg Dis

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Foot‐and‐mouth disease (FMD) is a highly contagious vesicular disease that is caused by the FMD virus (FMDV). This disease affects both wild and domestic cloven‐hoofed animals, and the latter of which includes cattle, swine, sheep and goats. FMD is endemic to Jordan and has a severe impact on the productivity of domestic livestock. In January 2017, FMD outbreaks were detected in different animal species across Jordan, resulting in high mortality rates among young lamb and goat populations as well as causing classic FMD symptoms in cattle. In this study, clinical specimens were collected from animals affected by FMD. The results obtained from sequencing the VP1 gene place the studied FMDV isolate within the FMDV O/ME‐SA/ Ind2001e sublineage. Phylogenetic analysis of VP1 suggests that the O/JOR/1/2017 isolate is very similar to that of viruses isolated from Saudi Arabia in 2016. The possible introduction of this strain to Jordan might occur through transboundary animal movement or other transmission routes from Saudi Arabia, a neighbouring country.

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“…During an outbreak, prevention of FMD from spreading can be done with the help of emergency vaccinations. There is continuous development of new vaccines but it is labor and difficult to develop a new vaccine whenever a new virus appears [52,53,54]. Therefore, many kinds of research have been conducted to develop advanced vaccines that can respond to evolving versions of the virus [55,56].…”

Section: De-population Of Infected Animalsmentioning

confidence: 99%

“…Therefore, many kinds of research have been conducted to develop advanced vaccines that can respond to evolving versions of the virus [55,56]. Current problems with FMD vaccines include antigens losses during the process of purification, unable to maintain the antibodies, low immunogenicity and narrow protection range of the antigens [57]. Economic impact of FMD FMD is a highly contagious Transboundary animal disease which effects the clovenhoofed animals.…”

Section: De-population Of Infected Animalsmentioning

confidence: 99%

A review on foot and mouth disease in dairy animals, etiology, pathogenesis and clinical findings

Azeem¹

2020

PAB

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Foot-and-mouth disease (FMD) is an extremely contagious disease of angulated animals and in livestock, it is an important pathogen more than 120 years after it was recognized. The virus of this disease belong to a genus Aphthovirus of the family picornaviridae and present as seven serotypes C, O, A, SAT1, SAT2, SAT3, and Asia1. Transmission of this disease occurs by direct and indirect contact, ingestion and by aerosols. The best multiplication sites of this virus are oral cavity, udder, heart, feet, and oro-pharynx. Specific, sensitive and quick diagnostic tools are required for effective control of this disease. FMD causes fever, salivation, anorexia and vesicular eruption on teats, feet, and mouth. In FMDV (Foot and Mouth disease Virus) endemic areas, annual production losses and vaccination estimated US$6.5-US$21 billion. Currently, the techniques which are used for diagnosis of FMD are Sandwich-ELISA (S-ELISA), Virus Isolation (VI), indirect ELISA (DIVA), real time-PCR and Liquid-Phase Blocking ELISA (LPBE) can be used for recognition of antibody against nonstructural proteins. The techniques which are used for quick and specific detection of FMDV are microarray and recombinant antigen-based detection, biosensor, Nucleotide sequencing, phage display and nucleic-acid-based diagnostic for serotyping. This review provides information about the FMD in Pakistan as many cases are reported in Pakistan and lead to morbidity and mortality of many animals. This review helps the reader to handle the cases practically in the field and helps the researchers to analyze the comprehensive picture of the FMD and in future researchers try to minimize such cases after reading this in Pakistan.

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Selection of vaccine strains for serotype O foot-and-mouth disease viruses (2007–2012) circulating in Southeast Asia, East Asia and Far East

Cited by 40 publications

References 43 publications

Outbreaks of foot and mouth disease in Egypt: Molecular epidemiology, evolution and cardiac biomarkers prognostic significance

Outbreaks of foot and mouth disease in Egypt: Molecular epidemiology, evolution and cardiac biomarkers prognostic significance

First detection of foot‐and‐mouth disease virus O/ME‐SA/ Ind2001e sublineage in Jordan

A review on foot and mouth disease in dairy animals, etiology, pathogenesis and clinical findings

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