Selection of extraction conditions of phenolic compounds from rambutan (Nephelium lappaceum L.) peel

Phuong, Nguyen Nhat Minh; Le, Thien Trung; DANG, MINH QUAN; Camp, John Van; Raes, Katleen

doi:10.1016/j.fbp.2020.05.008

Cited by 28 publications

(21 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Although water and ethanol (EtOH) are the most commonly used solvents in the cosmetic, food, and pharmaceutical industries, authors have often highlighted MeOH as the best solvent for the quantitative extraction of bioactive components, such as phenolic acids, from various natural sources [ 43 , 44 ]. Our previous studies have shown that the isomerization of phenolic acids (e.g., rosmarinic acid) was carried out to a greater extent in protic solvents such as MeOH, but not in THF as an aprotic solvent [ 36 ].…”

Section: Resultsmentioning

confidence: 99%

Validated Stability-Indicating GC-MS Method for Characterization of Forced Degradation Products of Trans-Caffeic Acid and Trans-Ferulic Acid

2021

View full text Add to dashboard Cite

When dealing with simple phenols such as caffeic acid (CA) and ferulic acid (FA), found in a variety of plants, it is very important to have control over the most important factors that accelerate their degradation reactions. This is the first report in which the stabilities of these two compounds have been systematically tested by exposure to various different factors. Forced degradation studies were performed on pure standards (trans-CA and trans-FA), dissolved in different solvents and exposed to different oxidative, photolytic and thermal stress conditions. Additionally, a rapid, sensitive, and selective stability-indicating gas chromatographic-mass spectrometric method was developed and validated for determination of trans-CA and trans-FA in the presence of their degradation products. Cis-CA and cis-FA were confirmed as the only degradation products in all the experiments performed. All the compounds were perfectly separated by gas chromatography (GC) and identified using mass spectrometry (MS), a method that additionally elucidated their structures. In general, more protic solvents, higher temperatures, UV radiation and longer storage times led to more significant degradation (isomerization) of both trans-isomers. The most progressive isomerization of both compounds (up to 43%) was observed when the polar solutions were exposed to daylight at room temperature for 1 month. The method was validated for linearity, precision as repeatability, limit of detection (LOD) and limit of quantitation (LOQ). The method was confirmed as linear over tested concentration ranges from 1−100 mg L−1 (r2s were above 0.999). The LOD and LOQ for trans-FA were 0.15 mg L−1 and 0.50 mg L−1, respectively. The LOD and LOQ for trans-CA were 0.23 mg L−1 and 0.77 mg L−1, respectively.

show abstract

Section: Resultsmentioning

confidence: 99%

Validated Stability-Indicating GC-MS Method for Characterization of Forced Degradation Products of Trans-Caffeic Acid and Trans-Ferulic Acid

2021

View full text Add to dashboard Cite

show abstract

“…A study, carried out by Phuong et al [ 27 ], found that UAE was effective in the extraction of polyphenolic compounds from rambutan peel of the Java variety (Can Tho City, Vietnam), achieving a total polyphenolic content of 0.14–0.16 mg per g of rambutan peel. By using the same technology, the Mexican variety yielded 0.17 mg per g of rambutan peel.…”

Section: Resultsmentioning

confidence: 99%

Recovery of Bioactive Ellagitannins by Ultrasound/Microwave-Assisted Extraction from Mexican Rambutan Peel (Nephelium lappaceum L.)

et al. 2022

View full text Add to dashboard Cite

Rambutan (Nephelium lappaceum L.) is a tropical fruit from Asia which has become the main target of many studies involving polyphenolic analysis. Mexico produces over 8 million tons per year of rambutan, generating a huge amount of agro-industrial waste since only the pulp is used and the peel, which comprises around 45% of the fruit’s weight, is left behind. This waste can later be used in the recovery of polyphenolic fractions. In this work, emerging technologies such as microwave, ultrasound, and the hybridization of both were tested in the extraction of phenolic compounds from Mexican rambutan peel. The results show that the hybrid technology extraction yielded the highest polyphenolic content (176.38 mg GAE/g of dry rambutan peel). The HPLC/MS/ESI analysis revealed three majoritarian compounds: geraniin, corilagin, and ellagic acid. These compounds explain the excellent results for the biological assays, namely antioxidant activity evaluated by the DPPH, ABTS, and LOI (Lipid oxidation inhibition) assays that exhibited great antioxidant capacity with IC50 values of 0.098, 0.335, and 0.034 mg/mL respectively, as well as prebiotic activity demonstrated by a µMax (maximum growth) of 0.203 for Lactobacillus paracasei. Lastly, these compounds have shown no hemolytic activity, opening the door for the elaboration of different products in the food, cosmetic, and pharmaceutical industries.

show abstract

“…Tais resultados são comparáveis aos já previamente relatados por Barreto, Benassi & Mercadante (2009) Provavelmente, as diferenças aqui descritas também foram associadas aos métodos extrativos. Apesar da sua boa eficiência, o teor total de composto fenólicos é diretamente afetado pela polaridade e seletividade do solvente, método extrativo, pH e temperatura (Yalavarthi, 2016;Shahidi et al, 2020;Phuong et al, 2020). É interessante notar que outras pesquisas relacionadas na literatura apresentaram teores inferiores de polifenóis para muitas das frutas consumidas no Brasil, quando comparados ao achado no extrato aquoso da polpa do pequi do presente estudo (Albuquerque Research, Society and Development, v. 9, n. 11, e2859119781, 2020(CC BY 4.0) | ISSN 2525-3409 | DOI: http://dx.doi.org/10.33448/rsd-v9i11.9781 et al, 2019Alara et al, 2019).…”

Section: Discussionunclassified

Determinação da atividade antioxidante e de fenóis totais do pequi (Caryocar brasiliense Camb.)

Denger

Kawano

Paula

et al. 2020

RSD

View full text Add to dashboard Cite

Antioxidantes naturais em frutas recebem enorme atenção da comunidade científica mundial devido seu papel na prevenção e no controle de doenças associadas ao estresse oxidativo. O objetivo deste estudo foi avaliar a atividade antioxidante das diferentes concentrações do extrato aquoso obtido da polpa do pequi, utilizando a combinação de diferentes metodologias. A partir de 4 % (g/dL) de tal extrato foi determinada a concentração de compostos fenólicos totais e a análise in vitro do potencial antioxidante pelos ensaios da atividade sequestrante do radical 2,2-difenil-1-picril-hidrazila (DPPH) e poder redutor de metais. Para a avaliação ex vivo, determinou-se em homogeneizado de cérebro de ratos a capacidade de inibição da peroxidação lipídica, estimada pela formação de substâncias reativas ao ácido tiobarbitúrico. O conteúdo fenólico total foi de 2,22 ± 0,045 g de equivalentes de ácido tânico/100 g. O teste de DPPH evidenciou que todas as frações das amostras processadas possuíram atividade em suas diferentes concentrações. Em relação a inibição da peroxidação lipídica, o teste de Tukey mostrou redução dos níveis, existindo diferença significativa (p<0,05) a partir da concentração de 0,02 g/dL. Os resultados ressaltam a importância do consumo de pequi e sugerem que, além do seu alto valor nutricional, apresenta excelentes propriedades bioativas e pode, portanto, ser uma estratégia promissora para o desenvolvimento de novas perspectivas agroindustriais.

show abstract

Selection of extraction conditions of phenolic compounds from rambutan (Nephelium lappaceum L.) peel

Cited by 28 publications

References 37 publications

Validated Stability-Indicating GC-MS Method for Characterization of Forced Degradation Products of Trans-Caffeic Acid and Trans-Ferulic Acid

Validated Stability-Indicating GC-MS Method for Characterization of Forced Degradation Products of Trans-Caffeic Acid and Trans-Ferulic Acid

Recovery of Bioactive Ellagitannins by Ultrasound/Microwave-Assisted Extraction from Mexican Rambutan Peel (Nephelium lappaceum L.)

Determinação da atividade antioxidante e de fenóis totais do pequi (Caryocar brasiliense Camb.)

Contact Info

Product

Resources

About