Selection of Cattle for Polymorphic Beta-Casein Gene in the Krasnodar Territory

Kovalyuk, N. V.; Satsuk, V. F.; Kovalyuk, M.; Machulskaya, E. V.

doi:10.31043/2410-2733-2019-1-22-26

Cited by 8 publications

(6 citation statements)

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“…It has 209 amino acids in at least 12 variants, which differ in their structures. The most common of these are A1 and A2 (Kovalyuk et al, 2018;Kovalyuk et al, 2019;Kononova et al, 2016;Kopylov et al, 2016). According to (Kučerova et al, 2006), four alleles (A1, A2, A3 and B) of the casein locus were detected in the genotyped animals.…”

Section: Biochemical Composition Of Milk and Caseinmentioning

confidence: 99%

“…Many scientists have determined the frequency of occurrence of A1 and A2 genotypes in different dairy cattle populations (Kovalyuk et al, 2018;Kovalyuk et al, 2019;Parashar and Saini, 2015;Kononova et al,2016;Barany et al, 1993;Ng-kwai-hang et al, 1986;Demirel and Çak, 2018;Kyselová et al, 2019;Kovalyuk et al, 2019). In particular, (Boro et al, 2016) reports that the frequency of the A1 allele in the Guernsey breed is in the range of 4-2%, in the Brown Swedish -34-30%, in the Jersey -50-37%, in the Holstein -56-47%, in the Ayrshire -60-51%, in the Red Danish -77%.…”

Section: Biochemical Composition Of Milk and Caseinmentioning

confidence: 99%

“…It is now scientifically proven that when digested with enzymes of the gastrointestinal tract of milk, which contains a fraction of beta-casein A1, peptide β-casomorphin 7 (BCM 7) is formed in a much larger amount than with the corresponding splitting of milk having a fraction of beta-casein A2 (Kovalyuk et al, 2019;Molee et al, 2015). It should be noted that this substance has opioid properties (Kononova et al, 2016).…”

Section: Biochemical Composition Of Milk and Caseinmentioning

confidence: 99%

“…In particular, New Zealand's A2 Milk Company licenses and markets all products of this milk in Australia, China and the US. According to the consumer surveys, the decisive factor in buying such a product is the actual selling price, which is based on the fact that A2 milk is taken at the price of organic milk (Kovalyuk et al, 2018;Kovalyuk et al, 2019;Mukhamadievа et al, 2016;Herbstreit, 2018).…”

Section: Biochemical Composition Of Milk and Caseinmentioning

confidence: 99%

“…Since these are dairy breeds, the main area of research was the analysis of productive qualities of livestock. Many scientists (Drozdov et al, 2009;Kopylov et al, 2016;Kovalyuk et al, 2019) consider native breeds of farm animals to be carriers of unique genetic information that cannot be reproduced by modern breeding methods. The study of their gene pool is conducted in terms of finding new useful genes of quantitative or other traits (productivity, disease resistance, stress) for use in further selection.…”

Section: Introductionmentioning

confidence: 99%

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Uso del polimorfismo del gen de la β-caseína en términos de preservación del ganado lechero marrón

2021

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Los componentes biológicamente importantes de la leche son la grasa, la proteína, la lactosa y los minerales. Gracias a ellos, es una parte significativa y esencial de la dieta humana. En los últimos años, entre los componentes de la proteína, la beta-caseína ha ganado gran importancia y popularidad entre las personas que se preocupan por su salud. Por lo tanto, la composición beta-caseína de proteínas lácteas y productos lácteos se ha convertido en una característica de cría importante de los animales lácteos. Este estudio tiene como objetivo evaluar las perspectivas para el uso del polimorfismo del locus de beta-caseína en la selección de ganado marrón para determinar la posibilidad de crear rebaños de piscina genética con características únicas de la leche – exclusivamente con beta-caseína A2. La estructura genética identificada de las vacas y toros de la raza Lebedyn por beta-caseína, la participación de los toros de la raza original de la raza suiza marrón (BS) según el modelo recíproco propuesto, permite formar poblaciones homocigotas de genotipos A2A2 en generaciones posteriores. Un enfoque individual para las cuestiones de coincidencia y selección, control, con la ayuda de métodos de diagnóstico de ADN, por los procesos de transmisión de genes de padres a descendientes, permitirá reponer rebaños con portadores del gen A2. El modelo de cría propuesto en combinación con el uso de espermatozoides sexados y el genotipado de novillas, tiene la mayor aceleración de selección de la creación de una población homocigota para beta-caseína A2A2.

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Section: Biochemical Composition Of Milk and Caseinmentioning

confidence: 99%

Section: Biochemical Composition Of Milk and Caseinmentioning

confidence: 99%

Section: Biochemical Composition Of Milk and Caseinmentioning

confidence: 99%

Section: Biochemical Composition Of Milk and Caseinmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Uso del polimorfismo del gen de la β-caseína en términos de preservación del ganado lechero marrón

2021

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Structure of Subpopulations of Ayrshire, Holstein, and Jersey Cattle in the Southern Regions of Russia by CSN2 (rs43703011), CSN3 (rs43703016), and Microsatellite Loci (BM1818, BM1824, BM2113, ETH10, ETH225, ETH3, INRA023, SPS115, TGLA126, TGLA122, TGLA227, TGLA53)

Kovalyuk,

Volchenko,

Shiryaeva

et al. 2024

Russ J Genet

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Structure of the holstein dairy cattle subpopulation in Russia by locus CSN2 and CSN3

Kovalyuk

Altukhova

Glushchenko

et al. 2022

jour

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Purpose: to determine the potential of the Russian subpopulation of the Holstein breed in relation to selection by loci of beta-and kappa-casein.Materials and methods. For loci CSN2 and CSN3, 1,539 Holstein cattle were genotyped, including 1,242 cows and heifers and 297 sires, and information on CSN2 and CSN3 genotypes of 297 US bulls was analyzed (World Wide Sires, Ltd).Results. It has been established that in the last two years there has been an increase in the percentage of sires in WWS with CSN2 genotypes A2A2 and CSN3 genotypes BB. Thus, sires allele frequency in the 2019 catalog was 0.51 and 0.29, respectively; and in the 2021 catalog was 0.68 and 0.31, respectively.Genotyped sires of domestic breeding organizations, which are mostly foreign origin, were characterized by predominance of the A2 allele CSN2; in this group the frequency of the allele was 0.63. However, the CSN3 B allele in the group of sires belonging to domestic organizations was found with a frequency of 0.34, which is 1.6 times lower than that of sires of American origin.In the genotyped group of Holstein cows and heifers (n = 1242) belonging to 3 large farms in the Krasnodar Krai, the gene frequency CSN2 allele A2 was minimal (0.57), and the CSN3 allele B (0.40) was higher than the allele frequency in the sires group of domestic breeding enterprises.Conclusion. At present, Russian breeding enterprises and farms are lagging behind in these indicators, however, by conducting targeted selection in accordance with the indicated trend, by selecting the appropriate breeding bulls, it is possible in the next generation to increase the proportion of animals carrying valuable genotypes.

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Selection of Cattle for Polymorphic Beta-Casein Gene in the Krasnodar Territory

Cited by 8 publications

References 0 publications

Uso del polimorfismo del gen de la β-caseína en términos de preservación del ganado lechero marrón

Uso del polimorfismo del gen de la β-caseína en términos de preservación del ganado lechero marrón

Structure of Subpopulations of Ayrshire, Holstein, and Jersey Cattle in the Southern Regions of Russia by CSN2 (rs43703011), CSN3 (rs43703016), and Microsatellite Loci (BM1818, BM1824, BM2113, ETH10, ETH225, ETH3, INRA023, SPS115, TGLA126, TGLA122, TGLA227, TGLA53)

Structure of the holstein dairy cattle subpopulation in Russia by locus CSN2 and CSN3

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